Gene:
mitogen-activated protein kinase kinase kinase kinase 4 (DBSS)
Gene ID:
133913
Symbol:
Map4k4_predicted
Species:
1182
Description:
OPN induces NIK/MEKK1-mediated JNK1-dependent/independent AP-1-mediated pro-MMP-9 activation and regulates the negative crosstalk between NIK/ERK1/2 and MEKK1/JNK1 pathways that ultimately controls the cell motility, invasiveness, and tumor growth