Gene:
BUB1 budding uninhibited by benzimidazoles 1 homolog beta (yeast)
Gene ID:
191675
Symbol:
BUB1B
Species:
1000
Description:
This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer.