Gene:
Cofactor of BRCA1
Gene ID:
191982
Symbol:
Species:
1000
Description:
Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counterated by the P-TEFb kinase complex. May be able to induce chromatin unfolding.