Gene:
deleted in lung and esophageal cancer 1
Gene ID:
192217
Symbol:
DLEC1
Species:
1000
Description:
The DLEC1 (deleted in lung cancer-1) gene contains 37 exons, spans approximately 59-kb, and is located in the 3p22-p21.3 chromosomal segment that is commonly deleted in various carcinomas. Several alternatively spliced DLEC1 transcripts contain disrupted coding regions and are likely to encode nonfunctional proteins. Aberrant transcription of DLEC1 may be involved in carcinogenesis of the lung, esophagus, and kidney.