Gene:
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isoenzyme B
Gene ID:
204084
Symbol:
MGAT4B
Species:
1000
Description:
Branching structures in complex N-glycans are synthesized on a common core structure of Man3GlcNAc2Asn in the Golgi apparatus by the N-acetylglucosaminyltransferases. The mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferases, which include isoenzyme A (MGAT4A) and isoenzyme B (MGAT4B), are key N-acetylglucosaminyltransferases regulating formation of tri- and other multiantennary structures. Alternative splicing of this gene results in two transcript variants encoding different isoforms.