Gene:
thrombopoietin (myeloproliferative leukemia virus oncogene ligand, megakaryocyte growth and development factor)
Gene ID:
206353
Symbol:
THPO
Species:
1000
Description:
Megakaryocytopoiesis is the cellular development process that leads to platelet production. The protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Alternatively spliced transcript variants encoding distinct isoforms have been reported.