Gene:
a disintegrin and metalloproteinase domain 2 (fertilin beta)
Gene ID:
192477
Symbol:
ADAM2
Species:
1000
Description:
This gene encodes a disintegrin and metalloprotease (ADAM) domain 2, which is a member of the ADAM protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a subunit of an integral sperm membrane glycoprotein (called fertilin), which plays an important role in sperm-egg interactions.