Gene:
neuralized-like 2 (Drosophila)
Gene ID:
206084
Symbol:
NEURL2
Species:
1000
Description:
Plays an important role in the process of myofiber differentiation and maturation. Essential component of the ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex, which mediates the ubiquitination of proteins. May contribute to catalysis through recognition and positioning of the substrate and the ubiquitin-conjugating enzyme. During myogenesis, controls the ubiquitination and degradation of the specific pool of CTNNB1/beta-catenin located at the sarcolemma (By similarity).