Gene:
aldehyde dehydrogenase 3 family, member B2
Gene ID:
205550
Symbol:
ALDH3B2
Species:
1000
Description:
The aldehyde dehydrogenases are a family of isozymes that may play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This particular family member is over 10 kb in length and consists of at least 10 exons. Although the gene is highly homologous to closely related family members, an earlier in-frame stop codon suggests several possibilities. It could represent a nonprocessed pseudogene, a functional gene where the premature stop codon is suppressed, or a gene product where a downstream in-frame ATG serves as the initiator codon. The expression of these transcripts is restricted to the salivary gland among the human tissues examined.