Gene:
PTK9 protein tyrosine kinase 9
Description:
This gene encodes twinfilin, an actin monomer-binding protein conserved from yeast to mammals. Studies of the mouse counterpart suggest that this protein may be an actin monomer-binding protein, and its localization to cortical G-actin-rich structures may be regulated by the small GTPase RAC1. Alternatively spliced transcript variants encoding distinct isoforms have been observed.