Gene:
amyloid beta (A4) precursor protein-binding, family B, member 3
Gene ID:
194371
Symbol:
APBB3
Species:
1000
Description:
The protein encoded by this gene is a member of the APBB protein family. It is found in the cytoplasm and binds to the intracellular domain of the Alzheimer's disease beta-amyloid precursor protein (APP) as well as to other APP-like proteins. It is thought that the protein encoded by this gene may modulate the internalization of APP. Six transcript variants encoding six different isoforms have been found for this gene.