Gene:
2',5'-oligoadenylate synthetase 1, 40/46kDa
Gene ID:
192750
Symbol:
OAS1
Species:
1000
Description:
This gene encodes an enzyme included in the 2', 5' oligoadenylate synthase family. This enzyme is induced by interferons and catalyzes the 2', 5' oligomers of adenosine in order to bind and activate RNase L. This enzyme family plays a significant role in the inhibition of cellular protein synthesis and viral infection resistance. Alternative splicing of this gene produces two isoforms which share identical N-terminal sequence but diverge at exon 7.