Gene:
reversion-inducing-cysteine-rich protein with kazal motifs
Gene ID:
190002
Symbol:
RECK
Species:
1000
Description:
The protein encoded by this gene is a cysteine-rich, extracellular protein with protease inhibitor-like domains whose expression is suppressed strongly in many tumors and cells transformed by various kinds of oncogenes. In normal cells, this membrane-anchored glycoprotein may serve as a negative regulator for matrix metalloproteinase-9, a key enzyme involved in tumor invasion and metastasis.