Gene:
a disintegrin and metalloproteinase domain 23
Description:
This gene encodes disintegrin and metalloprotease (ADAM) domain 23, which is a member of the ADAM protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Like ADAM22, this gene is highly expressed in the brain and may function as an integrin ligand in the brain. However, this gene and ADAM22 have different chromosomal localizations.