Gene:
ribosomal protein S6 kinase, 70kDa, polypeptide 2
Gene ID:
190640
Symbol:
RPS6KB2
Species:
1000
Description:
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates the S6 ribosomal protein and eucaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation. Alternate transcriptional splice variants encoding different isoforms have been found for this gene, but only two of them have been characterized to date.