Gene:
a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 6
Gene ID:
190978
Symbol:
ADAMTS6
Species:
1000
Description:
This gene encodes a disintegrin and metalloproteinase with thrombospondin motifs-6 (ADAMTS6), which is a member of the ADAMTS protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.