Gene:
WD40 repeat protein Interacting with phosphoInositides of 49kDa
Gene ID:
194643
Symbol:
Species:
1000
Description:
WD40 repeat proteins are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins, such as WIPI1, have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids (Proikas-Cezanne et al., 2004).[supplied by OMIM]