Gene:
SLAM family member 7
Gene ID:
194926
Symbol:
SLAMF7
Species:
1000
Description:
Isoform 1 mediates NK cell activation through a SAP- independent extracellular signal-regulated ERK-mediated pathway. May play a role in lymphocyte adhesion. Isoform 3 does not mediate any activation. SAP can bind the cytoplasmic tail of isoform 1 when phosphorylated in the presence of Fyn (in vitro).