Gene:
asparagine-linked glycosylation 8 homolog (yeast, alpha-1,3-glucosyltransferase)
Gene ID:
194962
Symbol:
ALG8
Species:
1000
Description:
The product of this gene belongs to the ALG6/ALG8 glucosyltransferase family. This enzyme adds the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Defects in this gene are the cause of congenital disorder of glycosylation type Ih (CDG-Ih). Alternatively spliced transcript variants encoding different isoforms have been identified.