Gene:
dickkopf homolog 1 (Xenopus laevis)
Gene ID:
195355
Symbol:
DKK1
Species:
1000
Description:
This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.