Gene:
Rab3 GTPase-activating protein, non-catalytic subunit (150kD)
Description:
Members of the RAB3 protein family (see RAB3A; MIM 179490) are implicated in Ca(2+)-dependent exocytosis. RAB3GAP, which is involved in regulation of RAB3 activity, is a heterodimeric complex consisting a 130-kD catalytic subunit (MIM 602536) and a 150-kD noncatalytic subunit (Nagano et al., 1998).[supplied by OMIM]