Gene:
2'-5'-oligoadenylate synthetase 2, 69/71kDa
Gene ID:
196250
Symbol:
OAS2
Species:
1000
Description:
This gene encodes an enzyme included in the 2', 5' oligoadenylate synthase family. This enzyme is induced by interferons and catalyzes the 2', 5' oligomers of adenosine in order to bind and activate RNase L. This enzyme family plays a significant role in the inhibition of cellular protein synthesis and viral infection resistance. Alternative splicing of this gene produces two isoforms which share a common 5' region but diverge in the 3' region.