Gene:
aldehyde reductase (aldose reductase) like 6
Description:
Aldo-keto reductases are widely distributed in mammalian tissues. ALDRL6, or myoinositol oxygenase (EC 1.13.99.1), is a renal-specific member of this family and catalyzes the first committed step in the only pathway of myoinositol metabolism. ALDRL6 has been implicated in complications of diabetes, including diabetic nephropathy.[supplied by OMIM]