Gene:
Rho guanine nucleotide exchange factor (GEF) 5
Gene ID:
196435
Symbol:
ARHGEF5
Species:
1000
Description:
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. This protein may be involved in the control of cytoskeletal organization. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.