Gene:
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26
Gene ID:
197565
Symbol:
DDX26
Species:
1000
Description:
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene is a candidate tumor suppressor gene and located in the critical region of loss of heterozygosity (LOH). It encodes a DEAD box protein, which is highly conserved in evolution, indicating an important cellular function.