Gene List

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Gene List
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Symbol Type Of Gene Taxonomy ID Gene ID Description View
FCER2 - The human leukocyte differentiation antigen CD23 (FCE2) is a key molecule for B-cell activation and growth. It is the low-affinity … View
PVT1 - - View
C1QTNF2 - - View
LTBR - The protein encoded by this gene is a member of the tumor necrosis factor (TNF) family of receptors. It is … View
- - Inhibitor of bone morphogenetic protein (BMP) function, it may regulate BMP responsiveness of osteoblasts and chondrocytes. View
DAZAP1 - In mammals, the Y chromosome directs the development of the testes and plays an important role in spermatogenesis. A high … View
VASP - Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that … View
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PREB - This gene encodes a protein that specifically binds to a Pit1-binding element of the prolactin (PRL) promoter. This protein may … View
COL8A1 - This gene encodes one of the two alpha chains of type VIII collagen. The gene product is a short chain … View
GPR8 - The protein encoded by this gene is an integral membrane protein and G protein-coupled receptor. The encoded protein is similar … View
PSMB5 - The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed … View
IL6 - - View
AMT - The enzyme system for cleavage of glycine (glycine cleavage system; EC 2.1.2.10), which is confined to the mitochondria, is composed … View
GPR73L1 - Prokineticins are secreted proteins that can promote angiogenesis and induce strong gastrointestinal smooth muscle contraction. The protein encoded by this … View
GNA14 - Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. View
OPTN - This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open … View
INHBC - This gene encodes the beta C chain of inhibin, a member of the TGF-beta superfamily. This subunit forms heterodimers with … View
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PRKCDBP - The protein encoded by this gene was identified as a binding protein of the protein kinase C, delta (PRKCD). The … View
SEPHS2 - This protein encodes an enzyme that synthesizes selenophosphate from selenide and ATP. Selenophosphate is the selenium donor used to synthesize … View
MAGEA4 - This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to … View
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HERC4 - HERC4 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 … View
PXMP4 - - View
SOX11 - This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of … View
MYL5 - This gene encodes one of the myosin light chains, a component of the hexameric ATPase cellular motor protein myosin. Myosin … View
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IRF2BP1 - - View
ABCC5 - The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport … View
MRPL37 - Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) … View
DAF - - View
FNDC6 - The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL22RA1/IL20RB dimer is a receptor for IL20 and … View
C9orf68 - - View
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NPL - - View
KIAA1012 - - View
NTS - This gene encodes a common precursor for two peptides, neuromedin N and neurotensin. Neurotensin is a secreted tridecapeptide, which is … View
TNFRSF18 - The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to have … View
DNM3 - Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular … View
CCL18 - This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 17. Cytokines are … View
ANAPC4 - A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates … View
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- - May function as an adapter molecule that regulates TRAF3-mediated JNK activation (By similarity). View
AAK1 - The protein encoded by this gene belongs to the Ser/Thr family of protein kinases SNF1 subfamily. There is strong evidence … View
TSFM - Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP … View
MFGE8 - Medin is the main constituent of aortic medial amyloid. View
CUL4B - Probably involved in ubiquitination and subsequent proteasomal degradation of target proteins. Plays a role in the polyubiquitination of CDT1 in … View
EXT1 - This gene encodes an endoplasmic reticulum-resident type II transmembrane glycosyltransferase involved in the chain elongation step of heparan sulfate biosynthesis. … View
KCNK4 - This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The … View
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COX6A2 - Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c … View
CDIPT - Phosphatidylinositol breakdown products are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell … View
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ETV6 - This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed … View
USP8 - Hydrolase that can remove conjugated ubiquitin from proteins and therefore plays an important regulatory role at the level of protein … View
RXRG - This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating … View
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MRPS10 - Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) … View
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TRIB3 - The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The … View
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CAMK2B - The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium … View
TATDN2 - - View
OPTC - Opticin belongs to class III of the small leucine-rich repeat protein (SLRP) family. Members of this family are typically associated … View
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RDH12 - Retinoids are indispensable light-sensitive elements of vision and also serve as essential modulators of cellular differentiation and proliferation in diverse … View
CLYBL - - View
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HLA-DPB1 - HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an … View
FAM13C1 - - View
CD58 - Ligand of the T lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent … View
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CTSC - The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears … View
- - This gene is unusual in that its coding sequence is derived almost entirely from a cluster of different Alu repeat … View
IQSEC1 - - View
DCP1A - Decapping is a key step in general and regulated mRNA decay. The protein encoded by this gene is a decapping … View
ZBTB5 - May be involved in transcriptional regulation. View
HSPB2 - - View
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WWP1 - WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety … View
CLEC4D - This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common … View
CPAMD8 - CPAMD8 belongs to the complement component-3 (C3; MIM 120700)/alpha-2-macroglobulin (A2M; MIM 103950) family of proteins, which are involved in innate … View
SOX6 - The SOX gene family encodes a group of transcription factors defined by the conserved high mobility group (HMG) DNA-binding domain. … View
SF3A3 - This gene encodes subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, … View
PTDSR - Required during embryogenesis and differentiation of multiple organs during embryogenesis. Probably acts as a key regulator of hematopoietic differentiation. May … View
SERPINA12 - - View
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KCNC4 - The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on … View
PERP - - View
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ATF7IP2 - - View
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C21orf127 - The protein encoded by this gene belongs to the methyltransferase superfamily. Alternative splicing occurs at this locus and two transcript … View
GJC1 - CX31.9 is a member of the large family of connexins that are required for the formation of gap junctions. Six … View
PES1 - This gene encodes a protein that is abnormally elevated in malignant tumors of astrocytic origin. It is a strongly conserved … View
RPP14 - Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'ends. View
LILRP2 - - View
PLEKHG1 - - View
PROC - - View
NUP107 - This gene encodes a member of the nucleoporin family. The protein is localized to the nuclear rim and is an … View
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Cbr1 - NADPH-dependent oxidoreductase that may be involved in ovarian follicular development [RGD] View
SMC1L1 - Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein … View
- - DCAL1 is a type II transmembrane, C-type lectin-like protein expressed on dendritic cells (DCs) and B cells. It interacts with … View
OSBP - Oxysterol binding protein is an intracellular protein that is believed to transport sterols from lysosomes to the nucleus where the … View
LRCH1 - - View
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POU3F4 - Probable transcription factor which exert its primary action widely during early neural development and in a very limited set of … View
SAFB2 - Binds to scaffold/matrix attachment region (S/MAR) DNA. Can function as an estrogen receptor corepressor and can also inhibit cell proliferation. View
STAM - This gene was identified by the rapid tyrosine-phosphorylation of its product in response to cytokine stimulation. The encoded protein contains … View
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DACT1 - Functions as an inhibitor of Dsh-mediated signaling pathways during development. By bindin to Dsh it may stabililize the beta-catenin degradation … View
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GSTA4 - Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular … View
AKR1C1 - This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. … View
IGHMBP2 - DNA-binding protein specific to 5'-phosphorylated single-stranded guanine-rich sequence related to the immunoglobulin mu chain switch region. Preferentially binds to the … View
APC - This gene encodes a tumor suppressor protein that includes among its many intracellular functions one of nuclear export. Defects in … View
RFP - The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three … View
IL23A - This gene encodes a subunit of the heterodimeric cytokine interleukin 23 (IL23). IL23 is composed of this protein and the … View
EPS15L1 - Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. View
MAGEA1 - This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to … View
SERPINA9 - - View
RHOB - Mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor … View
BEXL1 - - View
PLN - The protein encoded by this gene is found as a pentamer and is a major substrate for the cAMP-dependent protein … View
PAH - PAH encodes the enzyme phenylalanine hydroxylase that is the rate-limiting step in phenylalanine catabolism. Deficiency of this enzyme activity results … View
OSMR - Oncostatin M is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes … View
MDH1 - Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. … View
Nrgn - neuron specific protein kinase C substrate [RGD] View
CNTF - The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system … View
PLEKHA3 - Binds specifically to phosphatidylinositol-4-phosphate (PtdIns4P), but not to other phosphoinositides. View
UGT1A10 - This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, … View
CYP2J2 - This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze … View
C4orf10 - - View
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JUN - This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar … View
HMGB1 - Binds preferentially single-stranded DNA and unwinds double stranded DNA. View
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- - This gene encodes a protein with 5-phosphatase activity toward polyphosphate inositol. The protein localizes to the cytosol in regions lacking … View
DNAH14 - - View
FLT4 - Receptor for VEGFC. Has a tyrosine-protein kinase activity. View
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FCGRT - Binds to the Fc region of monomeric immunoglobulins gamma. Mediates the uptake of IgG from milk. Possible role in transfer … View
LOXL4 - LOXL4 is a member of the lysyl oxidase (LOX; MIM 153455) family of amine oxidases that catalyze the final enzymatic … View
SDCBP - The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin … View
- - This gene encodes a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein … View
AGBL3 - DISCONTINUED: LocusID:79914 was defined by AK023045.1 which contains repeat sequence and does not appear to represent a protein coding gene. View
VEGFB - Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by … View
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DHX29 - - View
MRPL9 - Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) … View
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MRPS2 - Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) … View
MTMR7 - Not known, could be a tyrosine-phosphatase. View
CDON - CDON and BOC (MIM 608708) are cell surface receptors of the immunoglobulin (Ig)/fibronectin type III (FNIII; see MIM 135600) repeat … View
ICMT - This gene encodes the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target … View
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PNLIPRP3 - - View
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ZNF689 - - View
ATE1 - This gene encodes an arginyltransferase, an enzyme that is involved in posttranslational conjugation of arginine to N-terminal aspartate or glutamate … View
STXBP3 - - View
PHF2 - This gene encodes a protein which contains a zinc finger-like PHD (plant homeodomain) finger, distinct from other classes of zinc … View
ST3GAL2 - The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from … View
ZBTB20 - May be a transcription factor that may be involved in hematopoiesis, oncogenesis, and immune responses. View
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FOXR2 - - View
AAAS - Plays a role in the normal development of the peripheral and central nervous system. View
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PMAIP1 - - View
P2RY14 - Receptor for UDP-glucose and other UDP-sugar coupled to G-proteins. Not activated by ATP, ADP, UTP or ATP. View
ALDH1A3 - Aldehyde dehydrogenase isozymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and … View
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- - Promotes in vitro the polymerization of tubulin into double-walled tubules and polymorphic aggregates or bundled stabilized microtubules blocks. When overexpressed, … View
RWDD2 - - View
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NRIP2 - - View
MCL1 - The protein encoded by this gene belongs to the Bcl-2 family. Alternative splicing occurs at this locus and two transcript … View
PPFIA3 - The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with … View
HAS2 - Hyaluronan or hyaluronic acid (HA) is a high molecular weight unbranched polysaccharide synthesized by a wide variety of organisms from … View
ATF5 - Transcriptional activator which binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters … View
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PCDH7 - This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The gene encodes a protein with … View
TP73 - Participates in the apoptotic response to DNA damage. When overproduced, activates transcription from p53-responsive promoters and induces apoptosis. May be … View
WEE1 - This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This … View
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PCYT1B - Controls phosphatidylcholine synthesis. View
CD33 - Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha2,6-linked sialic acid. The … View