| Hist1h1t |
- |
|
|
mouse homolog may play a role in chromatin structure and function [RGD]
|
View
|
| Ppp1r9a |
- |
|
|
binds to protein phosphatase type I and to actin filaments; involved in regulation of synaptic transmission [RGD]
|
View
|
| Foxa2 |
- |
|
|
This probe is non-specific and may hybridize to multiple genes. GeneID:128163/forkhead box A2; GeneID:153928/RGD1565745 (DBSS)
|
View
|
| Foxa3 |
- |
|
|
member of the Forkhead box a (Foxa) transcription factor family; binds rat proglucagon gene G2 promoter element [RGD]
|
View
|
| Igf1r |
- |
|
|
receptor for Igf-1; involved in induction of cell cycle progression and survival in many cell types [RGD]
|
View
|
| Ap3m1 |
- |
|
|
may act as an adaptor complex subunit; may play a role in intracellular transport [RGD]
|
View
|
| Emd |
- |
|
|
nuclear membrane protein; may be associated with spindle organization during mitosis; human homolog is associated with Emery-Dreifuss muscular dystrophy [RGD]
|
View
|
| Kcnh2 |
- |
|
|
voltage gated potassium channel pore forming subunit [RGD]
|
View
|
| Psmc5 |
- |
|
|
may play a role in ATP-dependent RNA/DNA unwinding [RGD]
|
View
|
| Rab26 |
- |
|
|
may play a role in vesicular transport [RGD]
|
View
|
| Olr837 |
- |
|
|
predicted member of the olfactory receptor family [RGD]
|
View
|
| Med4 |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| Naaladl1 |
- |
|
|
peptidase from rat ileum [RGD]
|
View
|
| Ccl20 |
- |
|
|
chemokine upregulated in ischemic brain tissue [RGD]
|
View
|
| Mafb |
- |
|
|
nuclear bZip transcription factor; involved in the late stages of chondrocyte development [RGD]
|
View
|
| Bst1 |
- |
|
|
expressed in pancreatic islet cells [RGD]
|
View
|
| Klk6 |
- |
|
|
a myelencephalon-specific protease which has trypsin-like substrate specificity; expressed in the nervous system [RGD]
|
View
|
| Ccr5 |
- |
|
|
G protein-coupled receptor; involved in regulation of leukocyte activation and migration [RGD]
|
View
|
| Edn2 |
- |
|
|
mediates vasoconstriction; may play a role in regulation of blood pressure [RGD]
|
View
|
| - |
- |
|
|
-
|
View
|
| Cyp7a1 |
- |
|
|
catalyzes the conversion of cholesterol, NADPH, and oxygen to 7-alpha-hydroxycholesterol, NADP(+) and water; plays a role in bile acid biosynthesis …
|
View
|
| Cacna1s |
- |
|
|
skeletal isoform and subunit of voltage dependent L-type Ca+2 channel; may mediate renal Ca+2 reabsorption; may play a role in …
|
View
|
| Cd4 |
- |
|
|
MHC class II binding protein that may be a candidate gene for collagen-induced arthritis; human CD4 is a receptor required …
|
View
|
| Cdk5 |
- |
|
|
serine/threonine kinase involved in synaptic regulation and neuronal development; phosphorylates synaptic protein Pctaire1; regulates acetylcholine receptor expression [RGD]
|
View
|
| Chrm2 |
- |
|
|
may inhibit cholinergic-mediated bronchoconstriction; may regulate bladder contraction [RGD]
|
View
|
| Ckm |
- |
|
|
catalyzes regeneration of ATP; expression is induced by p53 [RGD]
|
View
|
| Bdkrb1 |
- |
|
|
may play a role in regulation of inflammatory response [RGD]
|
View
|
| Tap1 |
- |
|
|
has similarity to multidrug resistant transporters; may transport antigenic peptides across the endoplasmic reticulum membrane in preparation for MHC class …
|
View
|
| Itgb7 |
- |
|
|
mediates adhesion to mucosal addressin cell adhesion molecule-1 (MAdCAM-1) [RGD]
|
View
|
| Ccbp2 |
- |
|
|
CC-chemokine receptor; may have a role in placental immunity or hematopoiesis [RGD]
|
View
|
| Akap4 |
- |
|
|
mouse homolog is a scaffold protein required for sperm motility and male fertility [RGD]
|
View
|
| Slc1a6 |
- |
|
|
mediates cotransport of one glutamate molecule with three Na+ ions and one H+ with countertransport of one K+ ion; also …
|
View
|
| Inpp4b |
- |
|
|
enzyme that catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4-trisphosphate, and inositol 3,4-bisphosphate [RGD]
|
View
|
| Ptgds2 |
- |
|
|
catalyzes the isomerization of prostaglandin H2 to prostaglandin D2 in prostaglandin biosynthesis [RGD]
|
View
|
| Kcnn3 |
- |
|
|
small-conductance Ca(2+)-activated K(+) channel; responsible for the afterhyperpolarization in neurons [RGD]
|
View
|
| Plec1 |
- |
|
|
cytoskeletal cross-linking protein; interacts with all three major groups of cytoskeletal proteins, actin filaments, microtubules, and intermediate filaments [RGD]
|
View
|
| Hif1a |
- |
|
|
regulates transcription in response to low oxygen; may play a role in vascular biology [RGD]
|
View
|
| Efna2 |
- |
|
|
ligand for ephrin receptors; involved in intrathymic T cell development [RGD]
|
View
|
| Hsd17b2 |
- |
|
|
17-beta hydroxysteroid enzyme that regulates the biological activity of sex hormones, including estrogen and androgens [RGD]
|
View
|
| Pik3r1 |
- |
|
|
regulatory subunit of phosphatidylinositol 3-kinase; three splice variants have been identified that regulate phosphatidylinositol 3-kinase interactions and function [RGD]
|
View
|
| Pthr2 |
- |
|
|
binds parathyroid hormone and induces cAMP accumulation [RGD]
|
View
|
| Eif2b5 |
- |
|
|
subunit of eukaryotic initiation factor-2B, which plays a role in eukayrotic initiation factor 2 (eIF-2) recycling in translation initiation [RGD]
|
View
|
| Lnpep |
- |
|
|
a zinc-dependent aminopeptidase that interacts with acyl-coenzyme A (CoA) dehydrogenases and plays a role in retention of GLUT4-containing vesicles to …
|
View
|
| Ptpn5 |
- |
|
|
a putative protein-tyrosine-phosphatase that is found enriched within the striatum [RGD]
|
View
|
| Acox2 |
- |
|
|
plays a role in fatty acid metabolism [RGD]
|
View
|
| Atp1b2 |
- |
|
|
plays a role in Na+ and K+ transport [RGD]
|
View
|
| Ear11 |
- |
|
|
cationic protein with similarity to human ECP; also has similarity to human eosinophil-derived neurotoxin and human ribonuclease k6 [RGD]
|
View
|
| Dll1 |
- |
|
|
homolog of the Notch Delta ligand; member of the delta/serrate/jagged family; may play a role in cell fate decisions during …
|
View
|
| Acvrl1 |
- |
|
|
may play a role in TGF-beta mediated transmembrane signaling in blood vessels [RGD]
|
View
|
| Smad1 |
- |
|
|
a transcriptional activator; activated by bone morphogenetic protein 4 (BMP4) [RGD]
|
View
|
| Smad3 |
- |
|
|
transcription factor; important component of the TGF-beta signaling pathway [RGD]
|
View
|
| Mras |
- |
|
|
small GTPase from skeletal muscle; may be involved in reorganization of the actin cytoskeleton [RGD]
|
View
|
| TPBG |
- |
|
|
-
|
View
|
| Cntn6 |
- |
|
|
glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule; may play a role in axonogenesis [RGD]
|
View
|
| Stc1 |
- |
|
|
calcium/phosphate-regulating protein; involved in stimulating osteoblast differentiation [RGD]
|
View
|
| Pcsk7 |
- |
|
|
may play a role in protein processing and maturation [RGD]
|
View
|
| Dlgap2 |
- |
|
|
transmembrane guanylate kinase protein; localized to postsynaptic densities in neuronal cells; may play a role in synaptogenesis [RGD]
|
View
|
| Ptpn12 |
- |
|
|
has protein tyrosine phosphatase activity [RGD]
|
View
|
| Epha3 |
- |
|
|
receptor tyrosine kinase; binds members of the ephrin-A family, ephrin-A2, -A3, -A4 and -A5 [RGD]
|
View
|
| Olr1500 |
- |
|
|
This probe is non-specific and may hybridize to multiple genes. GeneID:134784/olfactory receptor 1500; GeneID:170408/olfactory receptor 1504
|
View
|
| Cacnb4 |
- |
|
|
calcium channel subunit that plays a role in regulating the conductance of L-type voltage gated calcium channels [RGD]
|
View
|
| Capon |
- |
|
|
involved in regulating the interaction between neuronal nitric oxide synthase and PSD95 [RGD]
|
View
|
| SLIT1 |
- |
|
|
Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabaout …
|
View
|
| GZMB |
- |
|
|
Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target …
|
View
|
| SERPINB8 |
- |
|
|
-
|
View
|
| WDR48 |
- |
|
|
-
|
View
|
| SPTB |
- |
|
|
Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and …
|
View
|
| RBM16 |
- |
|
|
-
|
View
|
| Arnt2 |
- |
|
|
transcription factor; member of a family of transcription factors with a characteristic of basic helix-loop-helix (bHLH) motif contiguous with a …
|
View
|
| Arnt |
- |
|
|
may act as a transcription factor; mediates dioxin toxicity [RGD]
|
View
|
| MCM4 |
- |
|
|
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for …
|
View
|
| PLA2R1 |
- |
|
|
-
|
View
|
| SFRS2 |
- |
|
|
Necessary for the splicing of pre-mRNA. It is required for formation of the earliest ATP-dependent splicing complex and interacts with …
|
View
|
| - |
- |
|
|
-
|
View
|
| DLL1 |
- |
|
|
DLL1 is a human homolog of the Notch Delta ligand and is a member of the delta/serrate/jagged family. It plays …
|
View
|
| AADAT |
- |
|
|
This gene encodes a protein that is highly similar to mouse and rat kynurenine aminotransferase II. The rat protein is …
|
View
|
| KDELR2 |
- |
|
|
Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal …
|
View
|
| - |
- |
|
|
-
|
View
|
| Nf2 |
- |
|
|
has similarity to a protein family involved in linking cell membrane proteins to the cytoskeleton; may play a role in …
|
View
|
| Capn5 |
- |
|
|
member of a subset of the calpain family of proteases that lack a calmodulin-like domain [RGD]
|
View
|
| AKR1C2 |
- |
|
|
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. …
|
View
|
| - |
- |
|
|
-
|
View
|
| ITGB3 |
- |
|
|
The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha …
|
View
|
| PIP5K1B |
- |
|
|
-
|
View
|
| FBLN2 |
- |
|
|
This gene encodes an extracellular matrix protein, which belongs to the fibulin family. This protein binds various extracellular ligands and …
|
View
|
| SLC25A21 |
- |
|
|
SLC25A21 is a homolog of the S. cerevisiae ODC proteins, mitochondrial carriers that transport C5-C7 oxodicarboxylates across inner mitochondrial membranes. …
|
View
|
| LMCD1 |
- |
|
|
The protein encoded by this gene contains a cysteine-rich domain in the N-terminal region and 2 LIM domains in the …
|
View
|
| BRUNOL4 |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| MN1 |
- |
|
|
Meningioma 1 (MN1) contains two sets of CAG repeats. It is disrupted by a balanced translocation (4;22) in a meningioma, …
|
View
|
| RNF170 |
- |
|
|
-
|
View
|
| HIST1H3B |
- |
|
|
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure …
|
View
|
| CCL5 |
- |
|
|
This gene is one of several CC cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family …
|
View
|
| MSL3L1 |
- |
|
|
This gene encodes a nuclear protein and has similarity to drosophila male-specific lethal-3 gene. The drosophila protein plays a critical …
|
View
|
| STAT5A |
- |
|
|
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines …
|
View
|
| SLC38A3 |
- |
|
|
Sodium-dependent amino acid/proton antiporter. Mediates electrogenic cotransport of glutamine and sodium ions in exchange for protons. Also recognizes histidine, asparagine …
|
View
|
| C20orf44 |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| TNFRSF1B |
- |
|
|
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a …
|
View
|
| PC |
- |
|
|
This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active …
|
View
|
| SLC7A9 |
- |
|
|
Involved in the high-affinity, sodium-independent transport of cystine and neutral and dibasic amino acids (system b(0,+)-like activity). Thought to be …
|
View
|
| USP24 |
- |
|
|
Involved in the ubiquitin-dependent proteolytic pathway in conjunction with the 26S proteasome (By similarity).
|
View
|
| CACNA1A |
- |
|
|
Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of …
|
View
|
| - |
- |
|
|
-
|
View
|
| CYP3A4 |
- |
|
|
This gene, CYP3A4, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which …
|
View
|
| PTPLB |
- |
|
|
-
|
View
|
| PPIL5 |
- |
|
|
The protein encoded by this gene contains a leucine-rich repeat (LRR). It specifically interacts with TNFRSF9/4-1BB, a member of the …
|
View
|
| - |
- |
|
|
-
|
View
|
| FBXL19 |
- |
|
|
Members of the F-box protein family, such as FBXL19, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, …
|
View
|
| GTF2H2 |
- |
|
|
This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four …
|
View
|
| C14orf48 |
- |
|
|
-
|
View
|
| FNBP3 |
- |
|
|
May be involved in pre-mRNA splicing.
|
View
|
| PSMB6 |
- |
|
|
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed …
|
View
|
| VEGFC |
- |
|
|
The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is …
|
View
|
| Pcdh21 |
- |
|
|
non-classical cadherin gene which maybe involved in the formation and maintenance of neuronal network in the brain [RGD]
|
View
|
| NOMO2 |
- |
|
|
This gene encodes a protein originally thought to be related to the collagenase gene family. This gene is one of …
|
View
|
| MTP |
- |
|
|
MTP encodes the large subunit of the heterodimeric microsomal triglyceride transfer protein. Protein disulfide isomerase (PDI) completes the heterodimeric microsomal …
|
View
|
| GCAT |
- |
|
|
The degradation of L-threonine to glycine consists of a two-step biochemical pathway involving the enzymes L-threonine dehydrogenase and 2-amino-3-ketobutyrate coenzyme …
|
View
|
| PHGDHL1 |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| WFDC13 |
- |
|
|
This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. The WFDC domain, or WAP signature motif, …
|
View
|
| C18orf18 |
- |
|
|
-
|
View
|
| ABCA13 |
- |
|
|
Members of the ATP-binding cassette (ABC) transporter superfamily carry out energy-dependent transport of substrate molecules. ABCA13 belongs to a subfamily …
|
View
|
| - |
- |
|
|
-
|
View
|
| - |
- |
|
|
Potential oncogene and regulator of latent HIV. -------------------------------------------------------------------------- This Swiss-Prot entry is copyright. It is produced through a collaboration between …
|
View
|
| - |
- |
|
|
-
|
View
|
| PSMF1 |
- |
|
|
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core …
|
View
|
| C9orf140 |
- |
|
|
-
|
View
|
| - |
- |
|
|
DISCONTINUED: LocusID 85017 was defined by BC006164.1, which contains retroviral repeat sequence and does not appear to represent a protein …
|
View
|
| SGPL1 |
- |
|
|
Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Elevates stress-induced ceramide production and apoptosis.
|
View
|
| - |
- |
|
|
-
|
View
|
| C10orf85 |
- |
|
|
-
|
View
|
| PHF13 |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| ARF5 |
- |
|
|
ADP-ribosylation factor 5 (ARF5) is a member of the human ARF gene family. These genes encode small guanine nucleotide-binding proteins …
|
View
|
| OXT |
- |
|
|
There are two proteins encoded by this gene, oxytocin and neurophysin I. Oxytocin is posterior pituitary hormone which is synthesized …
|
View
|
| FAM11B |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| SERAC1 |
- |
|
|
-
|
View
|
| ART1 |
- |
|
|
ADP-ribosyltransferase catalyzes the ADP-ribosylation of arginine residues in proteins. Mono-ADP-ribosylation is a posttranslational modification of proteins that is interfered with …
|
View
|
| C19orf15 |
- |
|
|
-
|
View
|
| USP13 |
- |
|
|
-
|
View
|
| THBD |
- |
|
|
The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results …
|
View
|
| PKNOX2 |
- |
|
|
-
|
View
|
| CLCN6 |
- |
|
|
The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional …
|
View
|
| PHF22 |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| DLG3 |
- |
|
|
Interacts with the cytoplasmic tail of the NMDA receptor subunit NR2B (By similarity).
|
View
|
| C20orf77 |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| ULK3 |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| GPR26 |
- |
|
|
Orphan receptor.
|
View
|
| TTC21A |
- |
|
|
-
|
View
|
| MYST2 |
- |
|
|
Histone acetyltransferase which specifically represses AR-mediated transcription. May play a role in DNA replication.
|
View
|
| - |
- |
|
|
-
|
View
|
| CD164 |
- |
|
|
This is a carcinoma-associated protein, probably a mucin.
|
View
|
| RBM18 |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| ATP1A4 |
- |
|
|
The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of …
|
View
|
| ADCY1 |
- |
|
|
This gene encodes a form of adenylate cyclase expressed in brain. A similar protein in mouse is involved in pattern …
|
View
|
| - |
- |
|
|
-
|
View
|
| PRAP1 |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| GAL3ST4 |
- |
|
|
Sulfation is one of the most extensive modifications for glycan chains in glycoconjugates. GAL3ST4 belongs to a family of sulfotransferases …
|
View
|
| CCNB3 |
- |
|
|
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic …
|
View
|
| AP2A1 |
- |
|
|
This gene encodes the alpha 1 adaptin subunit of the adaptor protein 2 (AP-2) complex found in clathrin coated vesicles. …
|
View
|
| - |
- |
|
|
-
|
View
|
| ACYP2 |
- |
|
|
Acylphosphatase can hydrolyze the phosphoenzyme intermediate of different membrane pumps, particularly the Ca2+/Mg2+-ATPase from sarcoplasmic reticulum of skeletal muscle. Two …
|
View
|
| COL1A2 |
- |
|
|
This gene encodes one of the chains for type I collagen, the fibrillar collagen found in most connective tissues. Mutations …
|
View
|
| - |
- |
|
|
-
|
View
|
| RUSC1 |
- |
|
|
Putative signaling adapter which may play a role in neuronal differentiation. May be involved in regulation of NGF- dependent neurite …
|
View
|
| DOCK9 |
- |
|
|
Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP. Overexpression induces filopodia formation.
|
View
|
| ZNF307 |
- |
|
|
May function as a transcription factor.
|
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| C20orf50 |
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| TRIM41 |
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| CD82 |
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This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of …
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| FKBP8 |
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The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation …
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| DDR2 |
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Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved …
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| BCAT1 |
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This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of …
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| - |
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| RARRES1 |
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This gene was identified as a retinoid acid (RA) receptor-responsive gene. It encodes a type 1 membrane protein. The expression …
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| TBCA |
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Cofactor A is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly …
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| C19orf10 |
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The protein encoded by this gene was previously thought to support proliferation of lymphoid cells and was considered an interleukin. …
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| - |
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| PHKG2 |
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Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. This isozyme may regulate glycogeneolysis in …
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| - |
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| KLHL11 |
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| GABRG3 |
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GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening …
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| - |
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| MMP12 |
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Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such …
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| PFAS |
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Purines are necessary for many cellular processes, including DNA replication, transcription, and energy metabolism. Ten enzymatic steps are required to …
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| - |
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| HPS3 |
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This gene encodes a protein containing a potential clathrin-binding motif, consensus dileucine signals, and tyrosine-based sorting signals for targeting to …
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| MTA2 |
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This gene encodes a protein that has been identified as a component of NuRD, a nucleosome remodeling deacetylase complex identified …
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| KIAA0391 |
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