Gene List

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Gene List
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Symbol Type Of Gene Taxonomy ID Gene ID Description View
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THAP4 - - View
PAQR5 - Steroid membrane receptor. Binds progesterone. May be involved in oocyte maturation. View
- - When transfected into cell lines in which it is not expressed, suppresses cell growth. May play a role in tumor … View
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MAD1L1 - MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly … View
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KAZALD1 - Involved in the proliferation of osteoblasts during bone formation and bone regeneration (By similarity). View
- - TIP39 is related to parathyroid hormone (PTH; MIM 168450) and PTH-related protein (PTHRP; MIM 168470) and is a ligand for … View
CDCP1 - The protein encoded by this gene is a transmembrane protein containing three extracellular CUB domains. This protein is found to … View
PARD6A - Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in the formation of epithelial tight junctions. … View
ACTG1 - Actins are highly conserved proteins that are involved in various types of cell motility, and maintenance of the cytoskeleton. In … View
KIAA1600 - - View
MRPL10 - Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) … View
MCOLN3 - Mucolipins constitute a family of cation channel proteins with homologs in mouse, Drosophila, and C. elegans. Mutations in the human … View
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CCNL2 - - View
ABHD6 - - View
SLC35E4 - - View
FBXO22 - This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, … View
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OSBPL8 - This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Like most members, … View
MRPS5 - Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) … View
HAO2 - This gene is one of three related genes that have 2-hydroxyacid oxidase activity yet differ in encoded protein amino acid … View
UHMK1 - Upon serum stimulation, phosphorylates CDKN1B/p27Kip1, thus controlling CDKN1B subcellular location and cell cycle progression in G1 phase. May be involved … View
YWHAB - This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding … View
ZBTB10 - May be involved in transcriptional regulation. View
DMRT1 - This gene is found in a cluster with two other members of the gene family, having in common a zinc … View
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UBE2L3 - The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination … View
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FAM58A - - View
CNDP1 - This gene encodes a member of the M20 metalloprotease family. The encoded protein is specifically expressed in the brain, is … View
LIPI - - View
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LZIC - - View
GPR37 - Orphan receptor. View
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ARX - This gene is a homeobox-containing gene expressed during development. The expressed protein contains two conserved domains, a C-peptide (or aristaless … View
FAIM2 - Protects cells uniquely from Fas-induced apoptosis. View
SULT1C1 - Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in … View
RNF20 - The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. Yeast BRE1 is a ubiquitin ligase required … View
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C1orf56 - - View
REL - Proto-oncogene that may play a role in differentiation and lymphopoiesis. May function as a transcriptional transactivator. View
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PRG1 - This gene encodes a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of … View
ZNF212 - This gene belongs to the C2H2-type zinc finger gene family. The zinc finger proteins are involved in gene regulation and … View
PARP16 - - View
HAS3 - The protein encoded by this gene is involved in the synthesis of the unbranched glycosaminoglycan hyaluronan, or hyaluronic acid, which … View
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EHD3 - - View
TRIM3 - The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also called the 'RING-B-box-coiled-coil' (RBCC) … View
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LIFR - The leukemia inhibitory factor is a polyfunctional cytokine that affects the differentiation, survival, and proliferation of a wide variety of … View
MIF - This gene encodes a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation. It plays a role in the regulation of … View
HIST1H2BD - Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist … View
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PARP2 - This gene encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This … View
LIX1L - - View
SNAPC2 - Complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence … View
NME3 - Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP … View
ADRM1 - The protein encoded by this gene is an integral plasma membrane protein which promotes cell adhesion. The encoded protein is … View
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C20orf165 - - View
ADAM2 - This gene encodes a disintegrin and metalloprotease (ADAM) domain 2, which is a member of the ADAM protein family. Members … View
OVOL1 - This gene encodes a protein highly similar to Drosophila and mouse proteins. In Drosophila the ovo protein plays a critical … View
ACRV1 - This gene encodes a testis-specific, differentiation antigen, acrosomal vesicle protein 1, that arises within the acrosomal vesicle during spermatogenesis, and … View
RCL1 - Does not have cyclase activity. Plays a role in 40S- ribosomal-subunit biogenesis in the early pre-rRNA processing steps at sites … View
CSTA - The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while … View
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NPHP4 - This gene encodes a protein which contains a proline-rich region. The encoded protein may function in renal tubular development and … View
CCT5 - This gene encodes a molecular chaperone that is member of the chaperonin containing TCP1 complex (CCT), also known as the … View
WFDC2 - This gene generates 5 alternatively spliced transcript variants, which encode 5 different protein isoforms. These isoforms contain one or two … View
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SETDB2 - Proteins that contain a SET domain, such as SETDB2, modulate gene expression epigenetically through histone H3 (see MIM 601128) methylation. … View
TWIST1 - Basic helix-loop-helix (bHLH) transcription factors have been implicated in cell lineage determination and differentiation. The protein encoded by this gene … View
CLIC1 - Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial … View
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PSME2 - The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core … View
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CHRNA4 - The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at … View
PAPD5 - DNA polymerase, probably involved in DNA repair. May play a role in sister chromatid cohesion (By similarity). View
SSX3 - The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins … View
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CCL11 - This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a … View
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IBSP - The protein encoded by this gene is a major structural protein of the bone matrix. It constitutes approximately 12% of … View
EML5 - - View
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IMMT - - View
RBM11 - - View
IGHM - - View
LRDD - The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to … View
UBE1 - The protein encoded by this gene catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. This … View
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BPGM - Plays a major role in regulating hemoglobin oxygen affinity as a consequence of controlling 2,3-BPG concentration. Can also catalyze the … View
DO - This gene encodes a protein that contains a mono-ADP-ribosylation (ART) motif. It is a member of the ADP-ribosyltransferase gene family … View
SPATA5L1 - - View
RAB39 - May be involved in vesicular trafficking. View
WDR24 - - View
TUSC2 - This gene is a highly conserved lung cancer candidate gene. No other information about this gene is currently available. View
COX7AP2 - Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c … View
- - Ataxin-2 binding protein 1 has an RNP motif that is highly conserved among RNA-binding proteins. This protein binds to the … View
RALGDS - Stimulates the dissociation of GDP from the Ras-related RalA and RalB GTPases which allows GTP binding and activation of the … View
THRAP2 - The evolutionarily conserved THRAP genes encode a family of proteins that regulate embryonic development. THRAP2 is involved in early development … View
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LIG3 - Eukaryotes, in contrast to prokaryotes, contain more than one DNA ligase, and these enzymes have distinct roles in DNA metabolism. … View
GPR126 - Orphan receptor. View
C14orf109 - - View
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C20orf65 - - View
CLDN16 - Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and … View
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PROL1 - - View
BRCTD1 - - View
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ZNF225 - May function as a transcription factor. View
SLC12A7 - Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May mediate K(+) uptake into Deiters' cells in the cochlea and … View
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TAF1C - Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and … View
SLC39A10 - Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, … View
FGFR1OP2 - - View
AQP8 - Aquaporin 8 (AQP8) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the … View
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ZSCAN2 - The protein encoded by this gene contains several copies of zinc finger motif, which is commonly found in transcriptional regulatory … View
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SLCO3A1 - Mediates the Na(+)-independent transport of organic anions such as estrone-3-sulfate. View
ZNF12 - May function as a transcription factor. View
HDGF - Heparin-binding protein, with mitogenic activity for fibroblasts. View
MRPS36 - Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. The mitochondrial ribosome … View
STK17B - Acts as a positive regulator of apoptosis. View
ZNF281 - Involved in transcriptional regulation. Represses the transcription of a number of genes including gastrin and ornithine decarboxylase. Binds to the … View
GEMIN5 - GEMIN5 is part of a large macromolecular complex localized to both the cytoplasm and the nucleus that plays a role … View
PDZRN3 - - View
NCAM2 - The protein encoded by this gene belongs to the immunoglobulin superfamily. It is a type I membrane protein and may … View
ZNF306 - May function as a transcription factor. View
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TRPM6 - Essential ion channel and serine/threonine-protein kinase. Crucial for magnesium homeostasis. Has an important role in epithelial magnesium transport and in … View
IGJ - - View
SIRT2 - This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the … View
RGN - The protein encoded by this gene is a highly conserved, calcium-binding protein, that is preferentially expressed in the liver and … View
RAP1A - The product of this gene belongs to the family of RAS-related proteins. These proteins share approximately 50% amino acid identity … View
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VTN - The protein encoded by this gene is a member of the pexin family. It is found in serum and tissues … View
PEX3 - Involved in peroxisome biosynthesis and integrity. Assembles membrane vesicles before the matrix proteins are translocated. As a docking factor for … View
PPP1R12C - - View
SLC2A12 - - View
CASP3 - This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases … View
FLT3LG - Stimulates the proliferation of early hematopoietic cells. Synergizes well with a number of other colony stimulating factors and interleukins. View
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RPL27A - Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these … View
- - Required for 60S ribosomal subunit biogenesis (By similarity). View
LY6G6C - - View
HBQ1 - Theta-globin mRNA is found in human fetal erythroid tissue but not in adult erythroid or other nonerythroid tissue. The theta-1 … View
KIAA0423 - - View
TTLL4 - - View
HAVCR2 - CD4 (MIM 186940)-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of … View
AMMECR1 - - View
RNF138 - The protein encoded by this gene contains a RING finger, a motif present in a variety of functionally distinct proteins … View
RNF31 - The protein encoded by this gene contains a RING finger, a motif present in a variety of functionally distinct proteins … View
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UNG - This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating … View
PLEKHA9 - - View
ARFGEF2 - ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in … View
ATP1A3 - The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of … View
BLZF1 - Required for normal Golgi structure and for protein transport from the endoplasmic reticulum (ER) through the Golgi apparatus to the … View
PTEN - This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. … View
PPP1R10 - This gene encodes a protein with similarity to a rat protein that has an inhibitory effect on protein phosphatase-1 (PP1). … View
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TMEM29 - - View
RDX - Radixin is a cytoskeletal protein that may be important in linking actin to the plasma membrane. It is highly similar … View
TAGLN2 - The protein encoded by this gene is a homolog of the protein transgelin, which is one of the earliest markers … View
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ZDHHC4 - - View
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MBTPS2 - Intramembrane proteolysis of sterol-regulatory element- binding proteins (SREBPs) within the first transmembrane segment thereby releasing the N-terminal segment with a … View
DTNA - The protein encoded by this gene belongs to the dystrobrevin subfamily and the dystrophin family. This protein is a component … View
ZP2 - The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three … View
ADAR - This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double stranded RNA … View
PNPLA4 - - View
PAK4 - PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that … View
SIX4 - - View
RGS17 - This gene encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid … View
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PRDM2 - This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that … View
SLC7A8 - Sodium-independent, high-affinity transport of large neutral amino acids. Has higher affinity for L-phenylalanine that lat1. L-alanine is transported at physiological … View
THOC3 - TEX1 is part of the TREX (transcription/export) complex, which includes THO2 (MIM 300395), HPR1 (MIM 606930), ALY (MIM 604171), and … View
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PDE3A - Hydrolyzes both cyclic AMP (cAMP) and cyclic GMP (cGMP) (By similarity). View