Gene List

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Gene List
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Symbol Type Of Gene Taxonomy ID Gene ID Description View
PTPRO - This gene encodes a receptor-type protein tyrosine phosphatase containing a single intracellular catalytic domain with a characteristic signature motif. The … View
RNF135 - The protein encoded by this gene contains a RING finger domain, a motif present in a variety of functionally distinct … View
ITPKC - Inositol 1,4,5-trisphosphate 3-kinase (ITPK) catalyzes the phosphorylation of Ins(1,4,5)P3 to Ins(1,3,4,5)P4, both of which are modulators of calcium homeostasis. ITPK … View
- - Probably involved in membrane trafficking between the endoplasmic reticulum and the Golgi. View
MMD - This protein is expressed by in vitro differentiated macrophages but not freshly isolated monocytes. Although sequence analysis identifies seven potential … View
ZNF84 - May be involved in transcriptional regulation. View
OPRS1 - This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor … View
TCTEL1 - - View
NALP5 - This gene encodes a protein that belongs to the NALP family of cytoplasmic proteins. A mouse gene that encodes a … View
PLEC1 - The product of this gene belongs to the plakin or cytolinker family of genes. The encoded protein is involved in … View
MAGEC2 - This gene is related to members of the MAGEC gene family. It is not expressed in normal tissues, except for … View
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ZNF425 - - View
- - - View
- - - View
- - - View
- - - View
THSD6 - - View
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RFPL2 - - View
GNPAT - - View
- - - View
TBR1 - This gene is a member of a conserved family of genes that share a common DNA-binding domain, the T-box. T-box … View
TAF7 - The intronless gene for this transcription coactivator is located between the protocadherin beta and gamma gene clusters on chromosome 5. … View
C10orf57 - - View
NRBP - - View
CCL21 - This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family … View
LRRC3B - - View
DGKQ - The protein encoded by this gene contains three cysteine-rich domains, a proline-rich region, and a pleckstrin homology domain with an … View
CALB2 - Calbindin 2 (calretinin), closely related to calbindin 1, is an intracellular calcium-binding protein belonging to the troponin C superfamily. Calbindin … View
OPHN1 - Oligophrenin 1 has 25 exons and encodes a Rho-GTPase-activating protein. The Rho proteins are important mediators of intracellular signal transduction, … View
C6orf106 - - View
WDFY4 - - View
DNCI1 - The intermediate chains seem to help dynein bind to dynactin 150 kDa component. May play a role in mediating the … View
KIAA1161 - - View
ANXA10 - This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in … View
- - - View
SLC31A1 - Copper is an element essential for life, but excessive copper can be toxic or even lethal to the cell. Therefore, … View
- - - View
SNAG1 - This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which … View
MCART1 - - View
CTPS - The catalytic conversion of UTP to CTP is accomplished by the enzyme cytidine-5-prime-triphosphate synthetase. The enzyme is important in the … View
MRPL20 - Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) … View
COPZ1 - The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due … View
- - - View
RASGRF2 - RAS (MIM 190020) GTPases cycle between an inactive GDP-bound state and an active GTP-bound state. Guanine-nucleotide exchange factors (GEFs), such … View
EIF4EBP2 - Regulates eIF4E activity by preventing its assembly into the eIF4F complex. Mediates the regulation of protein translation by hormones, growth … View
SCO1 - Mammalian cytochrome c oxidase (COX) catalyzes the transfer of reducing equivalents from cytochrome c to molecular oxygen and pumps protons … View
SLC9A8 - Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding … View
SYNPO - Synaptopodin is an actin-associated protein that may play a role in actin-based cell shape and motility. The name synaptopodin derives … View
- - - View
TFB1M - The transcription of genes from mitochondrial DNA requires a mitochondrial RNA polymerase (see POLRMT, MIM 601778) and a DNA-binding transcription … View
ATAD1 - - View
APG9L1 - Plays a role in autophagy (By similarity). View
HSPA12A - - View
HSH2D - T-cell activation requires 2 signals: recognition of antigen by the T-cell receptor (see TCR; MIM 186880) and a costimulatory signal … View
- - - View
C15orf20 - - View
SMOC2 - - View
CCNF - This gene encodes a member of the cyclin family. Cyclins are important regulators of cell cycle transitions through their ability … View
- - - View
GBA3 - Cytosolic beta-glucosidase (EC 3.2.1.21) is a predominantly liver enzyme that efficiently hydrolyzes beta-D-glucoside and beta-D-galactoside but not any known physiologic … View
NDFIP1 - The protein encoded by this gene belongs to a small group of evolutionarily conserved proteins with three transmembrane domains. It … View
PILRA - Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes. SHP-1-mediated dephosphorylation of protein tyrosine residues is … View
FUT5 - May catalyze alpha-1,3 glycosidic linkages involved in the expression of VIM-2, Lewis X/SSEA-1 and sialyl Lewis X antigens. View
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ZDHHC8 - - View
COX7A1 - Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c … View
PTPN23 - May act as a negative regulator of Ras-mediated mitogenic activity. View
TRGV5 - - View
SCGB1A1 - Binds phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB) and weakly progesterone, potent inhibitor of phospholipase A2. View
DACH2 - Transcription factor that is involved in regulation of organogenesis. Seems to be a regulator for SIX1 and SIX6. Seems to … View
POLR3K - This gene encodes a small essential subunit of RNA polymerase III, the polymerase responsible for synthesizing transfer and small ribosomal … View
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U2AF1L2 - This gene encodes U2AF small subunit related protein 2 which is an essential splicing factor. This protein is associated with … View
IL31RA - - View
STEAP2 - - View
ZFP95 - This gene encodes a zinc finger protein of the Kruppel family. The protein contains a SCAN box and a KRAB … View
HKR2 - - View
ZNF493 - - View
- - - View
ZRANB3 - Members of the RAB3 protein family (see RAB3A; MIM 179490) are implicated in regulated exocytosis of neurotransmitters and hormones. RAB3GAP, … View
SMAP1 - The protein encoded by this gene is similar to the mouse stromal membrane-associated protein-1. This similarity suggests that this human … View
BTG4 - The protein encoded by this gene is a member of the BTG/Tob family. This family has structurally related proteins that … View
DAP - DAP gene encodes a basic, proline-rich, 15-kD protein. Death-associated protein acts as a positive mediator of programmed cell death that … View
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- - - View
WRNIP1 - Werner's syndrome is a rare autosomal recessive disorder characterized by premature aging. The protein encoded by this gene interacts with … View
FAM50A - May be a DNA-binding protein or transcriptional factor. View
- - - View
IFIT5 - - View
TAC3 - Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) … View
QKI - - View
BUB1 - This gene encodes a kinase involved in spindle checkpoint function. The kinase functions in part by phosphorylating a member of … View
TMEM16B - - View
PEX14 - Component of the peroxisomal translocation machinery with PEX13 and PEX17. Interacts with both the PTS1 and PTS2 receptors. Binds directly … View
PCANAP6 - - View
- - DISCONTINUED: LocusId 84344 was defined by AK026836.1, which contains LINE/L1 and SINE/Alu repeat sequences and does not appear to represent … View
KIAA0152 - - View
F8A1 - This gene is contained entirely within intron 22 of the factor VIII gene; spans less than 2 kb, and is … View
NR3C1 - The protein encoded by this gene is a receptor for glucocorticoids and can act as both a transcription factor and … View
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PIK3CB - Phosphorylates PtdIns, PtdIns4P and PtdIns(4,5)P2 with a preference for PtdIns(4,5)P2. View
NEU1 - The protein encoded by this gene encodes the lysosomal enzyme, which cleaves terminal sialic acid residues from substrates such as … View
COL9A3 - This gene encodes one of the three alpha chains of type IX collagen, the major collagen component of hyaline cartilage. … View
ARL8 - ARL8 belongs to a family of proteins that are structurally similar to ADP-ribosylation factors (ARFs; see MIM 103180). ARLs and … View
THAP6 - - View
MS4A1 - This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by … View
RHBDL2 - The protein encoded by this gene is a member of the rhomboid family of integral membrane proteins. This family contains … View
- - - View
RTN4RL1 - - View
TBCC - Cofactor C is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly … View
MAFK - The developmentally regulated expression of the globin genes depends on upstream regulatory elements termed locus control regions (LCRs). LCRs are … View
NDUFA11 - Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be … View
KCNG1 - Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their … View
FZD9 - Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD9 gene … View
- - - View
ZNF436 - May be involved in transcriptional regulation. View
C9orf46 - - View
PPIL3 - This gene encodes a member of the cyclophilin family. Cyclophilins catalyze the cis-trans isomerization of peptidylprolyl imide bonds in oligopeptides. … View
- - - View
ATXN7L2 - - View
ZNF600 - - View
LMO3 - - View
S100A4 - The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. … View
- - - View
- - - View
- - - View
FRAT2 - The protein encoded by this intronless gene belongs to the GSK-3-binding protein family. Studies show that this protein plays a … View
PTCH - This gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a … View
SLC35F2 - - View
FBXO36 - Members of the F-box protein family, such as FBXO36, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, … View
GYS1 - Transfers the glycosyl residue from UDP-Glc to the nonreducing end of alpha-1,4-glucan. View
- - - View
SPTLC1 - Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It converts L-serine and palmitoyl-CoA … View
SLC18A1 - Involved in the vesicular transport of biogenic amines. View
PLAC4 - - View
MT1F - Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both … View
GLI1 - This gene encodes a protein which is a member of the Kruppel family of zinc finger proteins. The function of … View
TAT - This nuclear gene encodes a mitochondrial protein tyrosine aminotransferase which is present in the liver and catalyzes the conversion of … View
CLPTM1 - - View
SOS2 - The RAS oncogene (MIM 190020) is mutated in nearly one-third of all human cancers. Members of the RAS superfamily are … View
EVL - Enhances actin nucleation and polymerization (By similarity). View
SNRPB2 - The protein encoded by this gene associates with stem loop IV of U2 small nuclear ribonucleoprotein (U2 snRNP) in the … View
SIX2 - May be involved in limb tendon and ligament development (By similarity). View
CDC42EP3 - CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The … View
HOXA7 - In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, … View
COL4A2 - This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. The … View
YME1L1 - The protein encoded by this gene is the human ortholog of yeast mitochondrial AAA metalloprotease, Yme1p. It is localized in … View
KCNJ15 - Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein … View
C9orf10OS - - View
FBXL10 - This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, … View
SFTPD - - View
CYP26A1 - This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze … View
- - - View
SEC11L1 - Part of the signal peptidase complex (SPC), exact function is not known. View
C21orf42 - - View
HRSP12 - Endoribonuclease responsible for the inhibition of the translation by cleaving mRNA. Inhibits cell-free protein synthesis. Cleaves phosphodiester bonds only in … View
- - Ghrelin is an endogenous ligand for the growth hormone secretagogue receptor (GHSR; MIM 601898) and is involved in regulating GH … View
LCN1 - The protein encoded by this gene belongs to the lipocalin family. Lipocalins are a group of extracellular proteins that are … View
C10orf84 - - View
IQCF2 - - View
BSCL2 - - View
TNFAIP6 - The protein encoded by this gene is a secretory protein that contains a hyaluronan-binding domain, and thus is a member … View
TESK1 - This gene product is a serine/threonine protein kinase that contains an N-terminal protein kinase domain and a C-terminal proline-rich domain. … View
- - - View
CHMP6 - - View
HDAC3 - Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and … View
C9orf80 - - View
- - - View
EDG6 - Endothelial differentiation, G-protein-coupled receptor 6 may regulate lymphocyte cell signaling. It is a member of the lysophospholipid/lysosphingolipid receptor family. View
C14orf169 - - View
TRAPPC6B - May play a role in vesicular transport from endoplasmic reticulum to Golgi (By similarity). View
GFM1 - Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for … View
ANKRD44 - - View
CBX1 - Heterochromatin protein-1 (HP1) is localized at heterochromatin sites, where it mediates gene silencing.[supplied by OMIM] View
- - - View
PRKACG - Cyclic AMP-dependent protein kinase (PKA) consists of two catalytic subunits and a regulatory subunit dimer. This gene encodes the gamma … View
H1F0 - Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist … View
OGFRL1 - - View
ENTPD3 - ENTPD3 is similar to E-type nucleotidases (NTPases). NTPases, such as CD39, mediate catabolism of extracellular nucleotides. ENTPD3 contains 4 apyrase-conserved … View
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C6orf68 - - View
C1orf64 - - View
- - - View
- - - View
ELA3B - Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes … View
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VCP - Valosin-containing protein (VCP) is a member of a family that includes putative ATP-binding proteins involved in vesicle transport and fusion, … View
SPRR1B - - View
- - - View
METAP1 - Removes the amino-terminal methionine from nascent proteins (By similarity). View
TNNI3K - - View
LRCH4 - This gene encodes a protein that contains leucine-rich repeats (LRR) at its amino terminus and that is known to be … View
SCGN - The encoded protein is a secreted calcium-binding protein which is found in the cytoplasm. It is related to calbindin D-28K … View
PRKAA2 - The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer … View
XYLB - The protein encoded by this gene shares 22% sequence identity with Hemophilus influenzae xylulokinase, and even higher identity to other … View
TAF13 - Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these … View