Gene List

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Gene List
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Symbol Type Of Gene Taxonomy ID Gene ID Description View
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RASGRP1 - RAS guanyl nucleotide-releasing protein (RASGRP) is a member of a family of genes characterized by the presence of a Ras … View
DYRK2 - DYRK2 belongs to a family of protein kinases whose members are presumed to be involved in cellular growth and/or development. … View
RPS25 - Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these … View
DTX3 - Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably … View
SLC25A22 - Involved in the transport of glutamate across the inner mitochondrial membrane. Glutamate is cotransported with H(+). View
CAV1 - The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell … View
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PTGFRN - Inhibits the binding of prostaglandin F2-alpha (PGF2- alpha) to its specific FP receptor, by decreasing the receptor number rather than … View
PCDHGB5 - This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome … View
C22orf5 - May activate the MAP kinase signaling pathway. View
ST13 - The protein encoded by this gene is an adaptor protein that mediates the association of the heat shock proteins HSP70 … View
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SLC2A4RG - The protein encoded by this gene is a nuclear transcription factor involved in the activation of the solute carrier family … View
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ZNF588 - May be involved in transcriptional regulation. View
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ABHD4 - - View
ADAMTSL2 - - View
CUTC - Involved in copper homeostasis (By similarity). View
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SLC4A5 - This gene encodes a member of the sodium bicarbonate cotransporter (NBC) family, part of the bicarbonate transporter superfamily. Sodium bicarbonate … View
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ZCCHC12 - - View
APG3L - APG8L (GABARAPL2 or GABARAP or MAP1LC3)-modifier protein conjugating enzyme involved in its E2-like covalent binding to PE. APG7L (E1-like enzyme) … View
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FZR1 - Regulates ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specifity upon the complex. The APC/C-Cdh1 … View
ARNT2 - The aryl hydrocarbon receptor nuclear translocator (ARNT; MIM 126110) is a member of a novel transcription factor family consisting of … View
CLTA - Clathrin is the main structural component of the lattice covering the cytoplasmic face of the coated pits and coated vesicles … View
- - May act as Rab effector protein and play a role in vesicle trafficking (By similarity). View
- - This gene encodes a protein that may function as a ribonuclease. An alternative splice variant has been described but its … View
C14orf73 - - View
PRODH2 - The protein encoded by this gene is similar to proline dehydrogenase (oxidase) 1, a mitochondrial enzyme which catalyzes the first … View
TBC1D21 - May act as a GTPase activating protein for Rab family protein(s). View
PARP4 - This gene encodes poly(ADP-ribosyl)transferase-like 1 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This … View
TBRG4 - - View
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UQCRC1 - This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of … View
ANAPC2 - A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates … View
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OASL - Does not have 2'-5'-OAS activity, but binds double- stranded RNA and DNA. View
GPLD1 - Many proteins are tethered to the extracellular face of eukaryotic plasma membranes by a glycosylphosphatidylinositol (GPI) anchor. The GPI-anchor is … View
LRFN1 - - View
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PCGF2 - The protein encoded by this gene contains a RING finger motif and is similar to the polycomb group (PcG) gene … View
ZNF643 - - View
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GRM4 - L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic … View
CREB1 - This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This … View
MAP3K14 - This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and … View
ENPP2 - Has a potent tumor cell motility-stimulating activity. View
DRD5P2 - - View
DLX5 - Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members … View
MLKL - - View
EVX1 - This gene encodes a protein that is a member of the vertebrate eve-related homeo box family. This protein acts as … View
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C5orf18 - - View
C6orf80 - This gene is located in a region close to the locus of the pseudogene of chemokine (C-C motif) receptor-like 1 … View
ZNF205 - May function as a transcription repressor. View
C14orf34 - - View
MAT2B - The protein encoded by this gene belongs to the methionine adenosyltransferase (MAT) family. MAT catalyzes the biosynthesis of S-adenosylmethionine from … View
COMMD9 - - View
GLI3 - This gene encodes a protein which belongs to the C2H2-type zinc finger proteins subclass of the Gli family. They are … View
TSPAN8 - The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. … View
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C9orf150 - - View
SHANK1 - Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic … View
NISCH - - View
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OR8G2 - Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a … View
SLC11A2 - Macrophage-specific membrane transport. Important in metal transport, in particular iron. View
KRTHA6 - The protein encoded by this gene is a member of the keratin gene family. As a type I hair keratin, … View
PNN - - View
KCNG2 - Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their … View
PEG3 - May function as a transcription factor. View
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HTR7 - The neurotransmitter, serotonin, is thought to play a role in various cognitive and behavioral functions. The serotonin receptor encoded by … View
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LGMN - This gene encodes a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be … View
NUDT14 - UDP-glucose (UDPG) acts as the sugar donor in numerous glycosylation reactions, including those involved in the production of glycogen. NUDT14 … View
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MPP6 - Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes … View
TMEM43 - - View
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SYT5 - May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may … View
VCPIP1 - Acts as a deubiquitinating enzyme. Necessary for VCP- mediated reassembly of Golgi stacks after mitosis. May play a role in … View
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MDS2 - - View
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RTTN - - View
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PBP - HCNP may be involved in the function of the presynaptic cholinergic neurons of the central nervous system. HCNP increases the … View
IRX4 - Likely to be an important mediator of ventricular differentiation during cardiac development. View
ADPGK - Catalyzes the phosphorylation of D-glucose to D-glucose 6-phosphate using ADP as the phosphate donor. GDP and CDP can replace ADP, … View
CD274 - Involved in the costimulatory signal, essential for T lymphocyte proliferation and production of IL10 and IFNG, in an IL2-dependent and … View
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RAB11FIP3 - Proteins of the large Rab GTPase family (see RAB1A; MIM 179508) have regulatory roles in the formation, targeting, and fusion … View
PLEK - Major protein kinase C substrate of platelets, its exact function is not known. View
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ZNF75 - May be involved in transcriptional regulation. View
ATXN10 - The autosomal dominant cerebellar ataxias (ADCAs) are a clinically and genetically heterogeneous group of disorders characterized by ataxia, dysarthria, dysmetria, … View
TMEM15 - - View
NBEA - This gene encodes a member of a large, diverse group of A-kinase anchor proteins that target the activity of protein … View
DHRS4 - Reduces all-trans-retinal and 9-cis retinal. Can also catalyze the oxidation of all-trans-retinol with NADP as co- factor, but with much … View
C17orf38 - - View
TMEPAI - - View
UBAP1 - This gene is a member of the UBA domain family, whose members include proteins having connections to ubiquitin and the … View
PCDHA6 - This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on … View
BAP1 - The protein encoded by this gene localizes to the nucleus and it interacts with the RING finger domain of the … View
OR4C1P - Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a … View
SORCS1 - This gene encodes one family member of vacuolar protein sorting 10 (VPS10) domain-containing receptor proteins. The VPS10 domain name comes … View
ZFP42 - - View
VMP - - View
SORL1 - This gene encodes a protein that belongs to the families of vacuolar protein sorting 10 (VPS10) domain-containing receptor proteins, of … View
PTDSS2 - Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine is replaced by L-serine. View
TNFSF7 - The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This … View
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RIMS2 - Rab effector involved in exocytosis. May act as scaffold protein. View
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BTNL3 - - View
TSPYL2 - - View
TP53INP1 - In response to double-strand DNA breaks, promotes p53/TP53 phosphorylation on Ser-46 and subsequent apoptosis. View
- - Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. View
ZNF536 - - View
WDFY2 - This gene encodes a protein that contains two WD domains and an FYVE zinc finger region. The function of this … View
CRH - Corticotropin-releasing hormone (CRH) is a 41-amino acid peptide derived from a 191-amino acid preprohormone. CRH is secreted by the paraventricular … View
CFTR - The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport … View
NDUFS4 - Complex I, or NADH:ubiquinone oxidoreductase, the first multisubunit enzyme complex of the mitochondrial respiratory chain, plays a vital role in … View
COL15A1 - This gene encodes the alpha chain of type XV collagen, a member of the FACIT collagen family (fibril-associated collagens with … View
ASCL1 - This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding … View
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UNC5B - UNC5B belongs to a family of netrin-1 (MIM 601614) receptors thought to mediate the chemorepulsive effect of netrin-1 on specific … View
C22orf8 - - View
ESRRBL1 - - View
GMFG - - View
GPX5 - Glutathione peroxidase (GPX)/glutathione reductase is part of the hydrogen peroxide scavenging system found within the epididymis in the mammalian male … View
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CHRDL1 - Seems to antagonize the function of BMP-4 by binding to it and preventing its interaction with receptors (By similarity). View
VN1R4 - - View
PHLDB3 - - View
PACSIN1 - May play a role in vesicle formation and transport. View
PLTP - The protein encoded by this gene is one of at least two lipid transfer proteins found in human plasma. The … View
- - Metallothioneins have a high content of cysteine residues that bind various heavy metals (By similarity). View
SLC38A6 - - View
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EYA3 - This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a … View
SLC4A1AP - - View
ZNF506 - - View
SAV1 - WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety … View
ZA20D2 - - View
TAS2R9 - This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These … View
SGPP1 - Has enzymatic activity against both sphingosine 1 phosphate (S1P) and dihydro-S1P. Regulates intracellular and extracellular S1P levels. View
AREG - The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth … View
HBA2 - The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes the following five loci: … View
AARS - The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA … View
STK24 - Protein kinase that act on both serine and threonine residues. View
FREQ - This gene is a member of the neuronal calcium sensor gene family, which encode calcium-binding proteins expressed predominantly in neurons. … View
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- - Participates in the FRAP1 pathway and associates in a near stoichiometric ratio with FRAP1 to form a nutrient-sensitive complex (NSC). … View
RAD9A - This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest … View
WDR57 - SPF38 is a component of the U5 small nuclear ribonucleoprotein (snRNP) particle. The U5 snRNP is part of the spliceosome, … View
ZNF683 - - View
PLRG1 - Necessary for spliceosome assembly and for pre-mRNA splicing. View
TAP1 - The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins … View
GATA3 - - View
MED6 - Plays a role in transcriptional coactivation. View
ID4 - Transcription factors containing a basic helix-loop-helix (bHLH) motif regulate expression of tissue-specific genes in a number of mammalian and insect … View
PDE4C - - View
- - This gene encodes a progestin-induced protein, which belongs to the HECT (homology to E6-AP carboxyl terminus) family. The HECT family … View
ELMOD2 - - View
FBXO41 - Members of the F-box protein family, such as FBXO41, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, … View
SERPINA1 - Alpha-1-antitrypsin is a protease inhibitor, deficiency of which is associated with emphysema and liver disease. The protein is encoded by … View
ZMYND19 - May be involved as a regulatory molecule in GPR24/MCH-R1 signaling. View
TFE3 - Positive-acting transcription factor that binds to the immunoglobulin enchancer MUE3 motif. It binds also very well to a USF/MLTF site. … View
LASS3 - May be involved in sphingolipid synthesis or its regulation (By similarity). View
AMN - The protein encoded by this gene is a type I transmembrane protein. It is thought to modulate bone morphogenetic protein … View
SET - Multitasking protein, involved in apoptosis, transcription, nucleosome assembly and histone binding. Isoform 2 anti-apoptotic activity is mediated by inhibition of … View
SLC22A14 - This gene encodes a member of the organic-cation transporter family. It is located in a gene cluster with another member … View
SLC6A19 - SLC6A19 is a system B(0) transporter that mediates epithelial resorption of neutral amino acids across the apical membrane in the … View
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GUCA2A - Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. View
SAT2 - Enzyme which catalyzes the acetylation of polyamines. Substrate specificity: norspermidine > spermidine = spermine >> N(1)acetylspermine = putrescine. View
PPARD - The protein encoded by this gene is a member of the peroxisome proliferator-activated receptor (PPAR) family. PPARs are nuclear hormone … View
DRD4 - This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits … View
SLC4A10 - - View
STARD9 - - View
IRF4 - Transcriptional activator. Binds to the interferon- stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda … View
C9orf12 - - View
KIAA1295 - - View
TLE6 - Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family … View
RIN1 - Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation. Can affect Ras … View
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