| - |
- |
|
|
-
|
View
|
| SLC24A5 |
- |
|
|
-
|
View
|
| LENG9 |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| ANKRD25 |
- |
|
|
-
|
View
|
| NDUFS8 |
- |
|
|
May donate electrons to ubiquinone.
|
View
|
| - |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| C9orf65 |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| TAL2 |
- |
|
|
-
|
View
|
| CD1D |
- |
|
|
CD1D is the sole group-2 member of the CD1 family of major histocompatibility (MHC)-like glycoproteins. See CD1A (MIM 188370) for …
|
View
|
| PLA2G4D |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| C1orf55 |
- |
|
|
-
|
View
|
| RG9MTD2 |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| CDR1 |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| ZNF589 |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| DNAH17 |
- |
|
|
-
|
View
|
| RAB5B |
- |
|
|
Protein transport. Probably involved in vesicular traffic (By similarity).
|
View
|
| - |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| CYB5 |
- |
|
|
Cytochrome b5 is a membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases.
|
View
|
| - |
- |
|
|
-
|
View
|
| PYY2 |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| CNNM1 |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| RBPMS2 |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| TRAFD1 |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| C14orf1 |
- |
|
|
-
|
View
|
| DUX4 |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| HIST1H2BC |
- |
|
|
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules …
|
View
|
| TNS3 |
- |
|
|
-
|
View
|
| DAB2 |
- |
|
|
DAB2 mRNA is expressed in normal ovarian epithelial cells but is down-regulated or absent from ovarian carcinoma cell lines. The …
|
View
|
| KIF13B |
- |
|
|
May be involved in reorganization of the cortical cytoskeleton. May be functionally important for the intracellular trafficking of MAGUKs and …
|
View
|
| - |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| TBCD |
- |
|
|
Cofactor D is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly …
|
View
|
| - |
- |
|
|
-
|
View
|
| PIM1 |
- |
|
|
The protooncogene PIM1 encodes a protein kinase upregulated in prostate cancer.[supplied by OMIM]
|
View
|
| - |
- |
|
|
-
|
View
|
| HOXA9 |
- |
|
|
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, …
|
View
|
| OR3A2 |
- |
|
|
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a …
|
View
|
| - |
- |
|
|
-
|
View
|
| CRYBB1 |
- |
|
|
Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate …
|
View
|
| OR10A5 |
- |
|
|
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a …
|
View
|
| MT3 |
- |
|
|
Binds heavy metals. Contains three zinc and three copper atoms per polypeptide chain and only a negligible amount of cadmium. …
|
View
|
| VRK1 |
- |
|
|
Serine/threonine kinase that phosphorylates Thr-18 of p53/TP53 and may thereby prevent the interaction between p53/TP53 and MDM2.
|
View
|
| FAM38A |
- |
|
|
-
|
View
|
| C1orf1 |
- |
|
|
This gene is a putative tumor suppressor gene.
|
View
|
| - |
- |
|
|
-
|
View
|
| RNF183 |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| GAGE4 |
- |
|
|
This gene belongs to a family of genes that are expressed in a variety of tumors but not in normal …
|
View
|
| TCF7L1 |
- |
|
|
Participates in the Wnt signaling pathway. Binds to DNA and acts as repressor in the absence of CTNNB1, and as …
|
View
|
| GRIPAP1 |
- |
|
|
GRASP1 is a neuron-specific guanine nucleotide exchange factor for the Ras family of small G proteins (RasGEF) and is associated …
|
View
|
| JUND |
- |
|
|
The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the …
|
View
|
| BTG3 |
- |
|
|
The protein encoded by this gene is a member of the BTG/Tob family. This family has structurally related proteins that …
|
View
|
| RPS6KA2 |
- |
|
|
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical …
|
View
|
| C6orf170 |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| STAR |
- |
|
|
The protein encoded by this gene plays a key role in the acute regulation of steroid hormone synthesis by enhancing …
|
View
|
| - |
- |
|
|
-
|
View
|
| TMEM14B |
- |
|
|
-
|
View
|
| SLC14A1 |
- |
|
|
-
|
View
|
| RPL31 |
- |
|
|
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these …
|
View
|
| PHF8 |
- |
|
|
-
|
View
|
| VEGF |
- |
|
|
Many polypeptide mitogens, such as basic fibroblast growth factor (FGFB; MIM 134920) and platelet-derived growth factors (MIM 173430, MIM 190040), …
|
View
|
| DLST |
- |
|
|
The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of 3 …
|
View
|
| - |
- |
|
|
-
|
View
|
| SUPV3L1 |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| DZIP1L |
- |
|
|
-
|
View
|
| USP45 |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| TRIM9 |
- |
|
|
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three …
|
View
|
| MAGEA10 |
- |
|
|
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to …
|
View
|
| PRNP |
- |
|
|
The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded …
|
View
|
| YWHAH |
- |
|
|
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This …
|
View
|
| TLL2 |
- |
|
|
This gene encodes an astacin-like zinc-dependent metalloprotease and is a subfamily member of the metzincin family. Unlike other family members, …
|
View
|
| SLC17A2 |
- |
|
|
May be involved in actively transporting phosphate into cells via Na(+) cotransport (By similarity).
|
View
|
| SNX15 |
- |
|
|
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which …
|
View
|
| SLC16A4 |
- |
|
|
Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo …
|
View
|
| - |
- |
|
|
This gene belongs to the HNRPG subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins …
|
View
|
| - |
- |
|
|
-
|
View
|
| SPRR2C |
- |
|
|
-
|
View
|
| AQP9 |
- |
|
|
The aquaporins/major intrinsic protein are a family of water-selective membrane channels. Aquaporin 9 has greater sequence similarity with AQP3 and …
|
View
|
| HNRPLL |
- |
|
|
May bind RNA and play a role in mRNA processing (By similarity).
|
View
|
| CYP2W1 |
- |
|
|
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze …
|
View
|
| KIR2DL1 |
- |
|
|
Receptor on natural killer (NK) cells for HLA-C alleles. Inhibits the activity of NK cells thus preventing cell lysis.
|
View
|
| PCNAP |
- |
|
|
-
|
View
|
| HES4 |
- |
|
|
-
|
View
|
| HECW1 |
- |
|
|
-
|
View
|
| GZMM |
- |
|
|
Human natural killer (NK) cells and activated lymphocytes express and store a distinct subset of neutral serine proteases together with …
|
View
|
| ITGA4 |
- |
|
|
The product of this gene belongs to the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins …
|
View
|
| HEBP2 |
- |
|
|
-
|
View
|
| ATP11A |
- |
|
|
The protein encoded by this gene is an integral membrane ATPase. The encoded protein is probably phosphorylated in its intermediate …
|
View
|
| - |
- |
|
|
The function of gene is not known, but it encodes an osmosis responsive factor. Identification of a conserved mouse homolog …
|
View
|
| - |
- |
|
|
-
|
View
|
| C22orf24 |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| LRRC37B |
- |
|
|
-
|
View
|
| OR12D2 |
- |
|
|
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a …
|
View
|
| ACOX1 |
- |
|
|
The protein encoded by this gene is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation …
|
View
|
| PARG |
- |
|
|
Poly(ADP-ribose) glycohydrolase (PARG) is the major enzyme responsible for the catabolism of poly(ADP-ribose), a reversible covalent-modifier of chromosomal proteins. The …
|
View
|
| MGAT4A |
- |
|
|
Branching structures in complex N-glycans are synthesized on a commom core structure of Man3GlcNAc2Asn in the Golgi apparatus by the …
|
View
|
| - |
- |
|
|
-
|
View
|
| PTGS1 |
- |
|
|
Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase …
|
View
|
| - |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| MAPT |
- |
|
|
This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA …
|
View
|
| - |
- |
|
|
-
|
View
|
| CTHRC1 |
- |
|
|
May act as a negative regulator of collagen matrix deposition (By similarity).
|
View
|
| - |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| UVRAG |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| CKAP2 |
- |
|
|
-
|
View
|
| FZD8 |
- |
|
|
This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that …
|
View
|
| HABP4 |
- |
|
|
-
|
View
|
| SLC12A6 |
- |
|
|
Mediates electroneutral potassium-chloride cotransport. May be activated by cell swelling. May contribute to cell volume homeostasis in single cells.
|
View
|
| - |
- |
|
|
This gene encodes a member of the hepatoma-derived growth factor (HDGF) family. Two alternatively spliced transcript variants encoding slightly different …
|
View
|
| CYP4B1 |
- |
|
|
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze …
|
View
|
| HIST1H2APS5 |
- |
|
|
-
|
View
|
| MAP3K15 |
- |
|
|
-
|
View
|
| HRH2 |
- |
|
|
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by …
|
View
|
| EZH2 |
- |
|
|
This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved …
|
View
|
| GOLPH2 |
- |
|
|
The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The …
|
View
|
| IGSF9 |
- |
|
|
-
|
View
|
| NLGN2 |
- |
|
|
This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as …
|
View
|
| - |
- |
|
|
-
|
View
|
| CXorf43 |
- |
|
|
-
|
View
|
| TAX1BP3 |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| KIAA1608 |
- |
|
|
-
|
View
|
| KCNB2 |
- |
|
|
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their …
|
View
|
| PIGV |
- |
|
|
-
|
View
|
| HMGCLL1 |
- |
|
|
-
|
View
|
| LRRC3 |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| C10orf47 |
- |
|
|
-
|
View
|
| WNT11 |
- |
|
|
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in …
|
View
|
| - |
- |
|
|
-
|
View
|
| SLC35D1 |
- |
|
|
Transports both UDP-glucuronic acid (UDP-GlcA) and UDP- N-acetylgalactosamine (UDP-GalNAc) from the cytoplasm to into the endoplasmic reticulum lumen. May participate …
|
View
|
| ZNF618 |
- |
|
|
-
|
View
|
| ARL9 |
- |
|
|
-
|
View
|
| TUBA2 |
- |
|
|
Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta …
|
View
|
| ALX4 |
- |
|
|
Transcription factor involved in skull and limb development.
|
View
|
| GFI1B |
- |
|
|
-
|
View
|
| HAS1 |
- |
|
|
Hyaluronan or hyaluronic acid (HA) is a high molecular weight unbranched polysaccharide synthesized by a wide variety of organisms from …
|
View
|
| ZNF420 |
- |
|
|
-
|
View
|
| COVA1 |
- |
|
|
The protein encoded by this gene is a growth-related cell surface protein. It was identifed because it reacts with the …
|
View
|
| TBC1D22A |
- |
|
|
May act as a GTPase activating protein for Rab family protein(s).
|
View
|
| SLC10A3 |
- |
|
|
This gene maps to a GC-rich region of the X chromosome and was identified by its proximity to a CpG …
|
View
|
| BPIL1 |
- |
|
|
This gene encodes a member of the lipid transfer/lipopolysaccharide binding protein (LT/LBP) gene family. It is highly expressed in hypertrophic …
|
View
|
| MAGEA3 |
- |
|
|
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to …
|
View
|
| SLC6A14 |
- |
|
|
SLC6A14 is a member of the Na(+)- and Cl(-)-dependent neurotransmitter transporter family and transports both neutral and cationic amino acids …
|
View
|
| BET3L |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| SEC6L1 |
- |
|
|
The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting …
|
View
|
| SCEL |
- |
|
|
The protein encoded by this gene is a precursor to the cornified envelope of terminally differentiated keratinocytes. This protein localizes …
|
View
|
| ZNF364 |
- |
|
|
-
|
View
|
| GFRA3 |
- |
|
|
The protein encoded by this gene is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor and a member of the GDNF receptor family. …
|
View
|
| ATRN |
- |
|
|
Multiple variants exist for this gene, three of which have been characterized and found to encode different isoforms. One of …
|
View
|
| MYH16 |
- |
|
|
The MYH16 gene, encoding a sarcomeric myosin heavy chain expressed in nonhuman primate masticatory muscles, is inactivated in humans. Stedman …
|
View
|
| MAPK4 |
- |
|
|
Mitogen-activated protein kinase 4 is a member of the mitogen-activated protein kinase family. Tyrosine kinase growth factor receptors activate mitogen-activated …
|
View
|
| LY6D |
- |
|
|
May be involved in cell-cell adhesion and signal transduction.
|
View
|
| UBL5 |
- |
|
|
Ubiquitin-like proteins (UBLs) are thought to be reversible modulators of protein function rather than protein degraders like ubiquitin (MIM 191339).[supplied …
|
View
|
| EIF4E2 |
- |
|
|
Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome …
|
View
|
| FOXK1 |
- |
|
|
-
|
View
|
| - |
- |
|
|
-
|
View
|
| FASN |
- |
|
|
The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate …
|
View
|
| SFRP5 |
- |
|
|
Secreted frizzled-related protein 5 (SFRP5) is a member of the SFRP family that contains a cysteine-rich domain homologous to the …
|
View
|
| CHRNA2 |
- |
|
|
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening …
|
View
|