Viewing Gene With DrugMatrix Data

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Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/
Symbol: FASTK
Name: Fas activated serinethreonine kinase
Location: 07q36.1
Locus Group: protein-coding gene
Gene Type: Protein Coding
Locus Type: gene with protein product
ID+ Clinical Trials CompTox DrugMatrix Conditions Design Enrollment Locations Outcomes
DrugMatrix Data: https://cebs.niehs.nih.gov/cebs/paper/15670
Gene | Activity | Annotation | GO | Identifier | Pathway | Signature | Simple | Tissue
Target | Accession | Expression | Synonym | Pathway Gene | Gene Platform | Pathway Target
DrugMatrix Gene Data For: 1 Matched Gene
Gene Name: Fas-activated serine/threonine kinase
Symbol:
View DrugMatrix Gene Data
Species: 1000
Description: The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined.