Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/
Symbol:
ERCC2
Name:
ERCC excision repair 2 TFIIH core complex helicase subunit
Location:
19q13.32
Locus Group:
protein-coding gene
Gene Type:
Protein Coding
Locus Type:
gene with protein product
DrugMatrix Data: https://cebs.niehs.nih.gov/cebs/paper/15670
DrugMatrix Gene Data For: 1 Matched Gene
Gene Name: excision repair cross-complementing rodent repair deficiency, complementation group 2 (xeroderma pigmentosum D)
Symbol:
Description: The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome.
