Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/
Symbol:
DKK1
Name:
dickkopf WNT signaling pathway inhibitor 1
Location:
10q21.1
Locus Group:
protein-coding gene
Gene Type:
Protein Coding
Locus Type:
gene with protein product
DrugMatrix Data: https://cebs.niehs.nih.gov/cebs/paper/15670
DrugMatrix Gene Data For: 1 Matched Gene
Gene Name: dickkopf homolog 1 (Xenopus laevis)
Symbol:
Description: This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.