Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/
Symbol:
CYLD
Name:
CYLD lysine 63 deubiquitinase
Location:
16q12.1
Locus Group:
protein-coding gene
Gene Type:
Protein Coding
Locus Type:
gene with protein product
DrugMatrix Data: https://cebs.niehs.nih.gov/cebs/paper/15670
DrugMatrix Gene Data For: 1 Matched Gene
Gene Name: cylindromatosis (turban tumor syndrome)
Symbol:
Description: Negative regulator of TRAF2 and NF-kappa-B signaling pathway. Has deubiquitinating activity that is directed towards non-Lys-48-linked polyubiquitin chains. The inhibition of NF- kappa-B activation is mediated at least in part, by the deubiquitination and inactivation of TRAF2 and, to a lesser extent, TRAF6.