Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/
Symbol:
ADRA1A
Name:
adrenoceptor alpha 1A
Location:
08p21.2
Locus Group:
protein-coding gene
Gene Type:
Protein Coding
Locus Type:
gene with protein product
DrugMatrix Data: https://cebs.niehs.nih.gov/cebs/paper/15670
DrugMatrix Gene Data For: 1 Matched Gene
Gene Name: adrenergic, alpha-1A-, receptor
Symbol:
Description: Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates 4 transcript variants, which encode 4 different isoforms with distinct C termini but having similar ligand binding properties.
