Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/
Symbol:
ADORA3
Name:
adenosine A3 receptor
Location:
01p13.2
Locus Group:
protein-coding gene
Gene Type:
Protein Coding
Locus Type:
gene with protein product
DrugMatrix Data: https://cebs.niehs.nih.gov/cebs/paper/15670
DrugMatrix Gene Data For: 1 Matched Gene
Gene Name: Adenosine A3 receptor
Symbol:
Description: There are 3 types of adenosine receptors, each of which contains 7 transmembrane domains and interacts with G proteins. The A1 receptors inhibit adenylate cyclase while the type A2 receptors stimulate activity. Each adenosine receptor has a specific pattern of ligand binding and a unique tissue distribution. Adenosine released during cardiac ischemia exerts a potent, protective effect in the heart. The adenosine A3 receptor is expressed on cardiac ventricular cells, and its activation protects the ventricular heart cell against injury during a subsequent exposure to ischemia.
