Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/
Symbol:
CREBBP
Name:
CREB binding protein
Location:
16p13.3
Locus Group:
protein-coding gene
Gene Type:
Protein Coding
Locus Type:
gene with protein product
DrugMatrix Data: https://cebs.niehs.nih.gov/cebs/paper/15670
DrugMatrix Gene Data For: 1 Matched Gene
Gene Name: CREB binding protein (Rubinstein-Taybi syndrome)
Symbol:
Description: Acetyltransferase enzyme. Acetylates histones, giving a specific tag for transcriptional activation. Also acetylates non- histone proteins, like NCOA3 coactivator. Mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. CBP, as coactivator, augments the activity of phosphorylated CREB to activate transcription of cAMP-responsive genes.