Viewing Gene With DrugMatrix Data


Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/

Symbol: XRCC1
Name: X-ray repair cross complementing 1
Location: 19q13.31
Locus Group: protein-coding gene
Gene Type: Protein Coding
Locus Type: gene with protein product

DrugMatrix Data: https://cebs.niehs.nih.gov/cebs/paper/15670
DrugMatrix Gene Data For: 1 Matched Gene
Gene Name: X-ray repair complementing defective repair in Chinese hamster cells 1
Symbol:
Species: 1000
Description: The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.