Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/
Symbol:
XIST
Name:
X inactive specific transcript
Location:
Xq13.2
Locus Group:
non-coding RNA
Gene Type:
Protein Coding
Locus Type:
RNA long non-coding
DrugMatrix Data: https://cebs.niehs.nih.gov/cebs/paper/15670
DrugMatrix Gene Data For: 1 Matched Gene
Gene Name: X (inactive)-specific transcript
Symbol:
Description: X inactivation is an early developmental process in mammalian females that transcriptionally silences one of the pair of X chromosomes, thus providing dosage equivalence between males and females. The process is regulated by several factors, including a region of chromosome X called the X inactivation center (XIC). The XIST gene is expressed exclusively from the XIC of the inactive X chromosome. The transcript is spliced but apparently does not encode a protein. The transcript remains in the nucleus where it coats the inactive X chromosome. Alternatively spliced transcript variants have been identified, but their full length sequences have not been determined. Mutations in the XIST promoter cause familial skewed X inactivation.
