Viewing Gene With DrugMatrix Data


Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/

Symbol: VPS35
Name: VPS35 retromer complex component
Location: 16q11.2
Locus Group: protein-coding gene
Gene Type: Protein Coding
Locus Type: gene with protein product

DrugMatrix Data: https://cebs.niehs.nih.gov/cebs/paper/15670
DrugMatrix Gene Data For: 1 Matched Gene
Gene Name: vacuolar protein sorting 35 (yeast)
Symbol:
Species: 1000
Description: This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex.