Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/
Symbol:
UHRF1
Name:
ubiquitin like with PHD and ring finger domains 1
Location:
19p13.3
Locus Group:
protein-coding gene
Gene Type:
Protein Coding
Locus Type:
gene with protein product
DrugMatrix Data: https://cebs.niehs.nih.gov/cebs/paper/15670
DrugMatrix Gene Data For: 1 Matched Gene
Gene Name: ubiquitin-like, containing PHD and RING finger domains, 1
Symbol:
Description: UHRF1 binds to an inverted CCAAT box in the promoter of topoisomerase II-alpha (TOP2A; MIM 126430). TOP2A introduces transient double-stranded breaks in DNA, which are required during the cell cycle for DNA replication, chromosome condensation, and segregation. UHRF1 is likely involved in TOPO2A expression (Hopfner et al., 2000).[supplied by OMIM]