Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/
Symbol:
TRAF5
Name:
TNF receptor associated factor 5
Location:
01q32.3
Locus Group:
protein-coding gene
Gene Type:
Protein Coding
Locus Type:
gene with protein product
DrugMatrix Data: https://cebs.niehs.nih.gov/cebs/paper/15670
DrugMatrix Gene Data For: 1 Matched Gene
Gene Name: TNF receptor-associated factor 5
Symbol:
Description: The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. This protein has been found to be one of the components of a multiple protein complex associated with the CD40 cytoplasmic domain, which mediates TNF induced NF-kappa B activation and protection from cell death. This protein has also been implicated in the signaling events mediated by various other receptors including CD27, CD30, and lymphotoxin-beta receptor. Two alternatively spliced transcript variants encoding the same protein have been reported.
