Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/
Symbol:
TIMP3
Name:
TIMP metallopeptidase inhibitor 3
Location:
22q12.3
Locus Group:
protein-coding gene
Gene Type:
Protein Coding
Locus Type:
gene with protein product
DrugMatrix Data: https://cebs.niehs.nih.gov/cebs/paper/15670
DrugMatrix Gene Data For: 1 Matched Gene
Gene Name: tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy, pseudoinflammatory)
Symbol:
Description: This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. The expression of this gene is induced in response to mitogenic stimulation and subject to cell cycle regulation. Mutations in this gene cause the autosomal dominant disorder Sorsby's fundus dystrophy.