Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/
Symbol:
TAF1A
Name:
TATA-box binding protein associated factor RNA polymerase I subunit A
Location:
01q41
Locus Group:
protein-coding gene
Gene Type:
Protein Coding
Locus Type:
gene with protein product
DrugMatrix Data: https://cebs.niehs.nih.gov/cebs/paper/15670
DrugMatrix Gene Data For: 1 Matched Gene
Gene Name: TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
Symbol:
Description: Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the smallest SL1-specific TAF. Two transcripts encoding different isoforms have been identified.