Viewing Gene With DrugMatrix Data

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Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/
Symbol: STAM2
Name: signal transducing adaptor molecule 2
Location: 02q23.3
Locus Group: protein-coding gene
Gene Type: Protein Coding
Locus Type: gene with protein product
ID+ Clinical Trials CompTox DrugMatrix Conditions Design Enrollment Locations Outcomes
DrugMatrix Data: https://cebs.niehs.nih.gov/cebs/paper/15670
Gene | Activity | Annotation | GO | Identifier | Pathway | Signature | Simple | Tissue
Target | Accession | Expression | Synonym | Pathway Gene | Gene Platform | Pathway Target
DrugMatrix Gene Data For: 1 Matched Gene
Gene Name: signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
Symbol:
View DrugMatrix Gene Data
Species: 1000
Description: The protein encoded by this gene is closely related to STAM, an adaptor protein involved in the downstream signaling of cytokine receptors, both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). Similar to STAM, this protein acts downstream of JAK kinases, and is phosphorylated in response to cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway downstream of JAK kinases upon cytokine stimulation.