Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/
Symbol:
SRD5A2
Name:
steroid 5 alpha-reductase 2
Location:
02p23.1
Locus Group:
protein-coding gene
Gene Type:
Protein Coding
Locus Type:
gene with protein product
DrugMatrix Data: https://cebs.niehs.nih.gov/cebs/paper/15670
DrugMatrix Gene Data For: 1 Matched Gene
Gene Name: steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
Symbol:
Description: Steroid 5-alpha reductase 2 is a microsomal protein expressed at high levels in androgen-sensitive tissues such as the prostate. This isoform is active at acidic pH and is sensitive to the 4-azasteroid inhibitor finasteride. Deficiencies can result in male pseudohermaphroditism, specifically pseudovaginal perineoscrotal hypospadias (PPSH).