Viewing Gene With DrugMatrix Data

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Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/
Symbol: CACNA1E
Name: calcium voltage-gated channel subunit alpha1 E
Location: 01q25.3
Locus Group: protein-coding gene
Gene Type: Protein Coding
Locus Type: gene with protein product
ID+ Clinical Trials CompTox DrugMatrix Conditions Design Enrollment Locations Outcomes
DrugMatrix Data: https://cebs.niehs.nih.gov/cebs/paper/15670
Gene | Activity | Annotation | GO | Identifier | Pathway | Signature | Simple | Tissue
Target | Accession | Expression | Synonym | Pathway Gene | Gene Platform | Pathway Target
DrugMatrix Gene Data For: 1 Matched Gene
Gene Name: calcium channel, voltage-dependent, alpha 1E subunit
Symbol:
View DrugMatrix Gene Data
Species: 1000
Description: This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. Alternate transcriptional splice variants of the gene described here have been observed but have not been thoroughly characterized.