Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/
Symbol:
PPY
Name:
pancreatic polypeptide
Location:
17q21.31
Locus Group:
protein-coding gene
Gene Type:
Protein Coding
Locus Type:
gene with protein product
DrugMatrix Data: https://cebs.niehs.nih.gov/cebs/paper/15670
DrugMatrix Gene Data For: 1 Matched Gene
Gene Name: pancreatic polypeptide
Symbol:
Description: Pancreatic polypeptide (PPY) was the first identified product of the dominating endocrine cell type of the duodenal pancreas (Kimmel et al., 1975; Larsson et al., 1976). This hormone of 36 amino acids seems to be involved in the regulation of exocrine pancreatic secretion and biliary tract motility (Schwartz, 1983). PPY may be important in regulation of food intake; genetically obese laboratory animals have altered PPY release and in New Zealand obese mice weight gain can be cured by infusion of PPY. Children with Prader-Willi syndrome (PWS; MIM 176270) have blunted secretion of PPY (Zipf et al., 1981).[supplied by OMIM]