Gene Data From HGNC: https://www.genenames.org/download/statistics-and-files/
Symbol:
PARP4
Name:
poly(ADP-ribose) polymerase family member 4
Location:
13q12.12
Locus Group:
protein-coding gene
Gene Type:
Protein Coding
Locus Type:
gene with protein product
DrugMatrix Data: https://cebs.niehs.nih.gov/cebs/paper/15670
DrugMatrix Gene Data For: 1 Matched Gene
Gene Name: poly (ADP-ribose) polymerase family, member 4
Symbol:
Description: This gene encodes poly(ADP-ribosyl)transferase-like 1 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. Since this protein is not capable of binding DNA directly, its transferase activity may be activated by other factors such as protein-protein interaction mediated by the extensive carboxyl terminus.
